1424388-05-5

Basic information

• Product Name: C₂₁H₂₃ClFN₅O₄
• CAS NO: 1424388-05-5
• Molecular Weight: 463.896
• Mol File: 1424388-05-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₂₃ClFN₅O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₂₃ClFN₅O₄(1424388-05-5)
• EPA Substance Registry System: C₂₁H₂₃ClFN₅O₄(1424388-05-5)

Safety Data

• Hazardous Substances Data: 1424388-05-5(Hazardous Substances Data)

Upstream product

• 371194-19-3 (5R)-3-(4-(4-Oxopiperidin-1-yl)-3-fluorophenyl)-5-(1,2,3-triazol-1-ylmethyl)oxazolidin-2-one 
• 7071-12-7 triethyl 2-chloro-2-phosphonoacetate 

Relevant articles and documents

Synthesis and antibacterial activities of new piperidine substituted (5R)-[1,2,3]triazolylmethyl and (5R)-[(4-F-[1,2,3]triazolyl)methyl] oxazolidinones

A novel series of 5(R)-[1,2,3]triazolylmethyl and (5R)-[(4-F-[1,2,3] triazolyl)methyl]oxazolidinones having various piperidine group were synthesized and evaluated antibacterial activity against clinically isolated resistant strains of Gram-positive and Gram-negative bacteria. The compound 12a having exo-cyanoethylidene group in the 4-position of piperidine ring was found to be two to threefold more potent than the linezolid against penicillin-resistant Staphylococcus pneumonia and Staphylococcus agalactiae, and also exhibited reduced MAO-B inhibitory activity.