142472-15-9Relevant articles and documents
Metal-Free, DBU-Mediated, Microwave-Assisted Synthesis of Benzo[c]xanthones by Tandem Reactions of Alkynyl-1,3-diketones
Liang, Yi-En,D. Barve, Balaji,Kuo, Yao-Haur,Fang, Hsu-Wei,Kuo, Ting-Shen,Li, Wen-Tai
supporting information, p. 505 - 511 (2020/12/01)
A base-mediated, green, microwave-assisted efficient preparation of a diverse benzoxanthone library from variety of readily accessible γ-alkynyl 1,3-diketones is reported. The synthesis is based on tandem reactions involving intramolecular cyclization, propargyl-allenyl isomerization, and electrocyclization in one pot. Some of the benzoxanthones are also synthesized by the one-pot reaction of 1,3-diketone and alkynyl bromide under basic heating conditions. This transformation also results in the construction of one new C?C bond and one new C?O bond. (Figure presented.).
New mononuclear Pd(II) complexes of sterically hindered bispyrazolylmethanes
Jones, Michael W.,Adlington, Robert M.,Baldwin, Jack E.,Le Pevelen, Delphine D.,Smiljanic, Nicolas
experimental part, p. 1097 - 1101 (2010/06/15)
Three new palladium(II) complexes incorporating the bispyrazolylmethane core have been synthesised and fully characterised in the solution and solid state. Single crystal X-ray studies revealed almost complete blocking of the upper face of the palladium ion by the substituents at the 3- and 5-positions of the pyrazole rings. Preliminary screening of the complexes for palladium(II) mediated catalysis revealed good catalytic activity for the Heck coupling reaction.
Synthesis of dibenzoylmethane derivatives and inhibition of mutagenicity in Salmonella typhimurium
Choshi,horimoto,Wang,Nagase,Ichikawa,Sugino,Hibino
, p. 1047 - 1049 (2007/10/02)
Twenty dibenzoylmethanes with methyl, methoxy, bromo, chloro, or fluoro substitution on either one or both benzene rings were synthesized and assayed for inhibition of the mutagenicity of 2-nitrofluorene in S. typhimurium TA98. 2,2-Dimethoxy, 3,3-dimethoxy and 3,3,4,4-tetramethoxydibenzoylmethane was as active as dibenzoylmethane. None of the halogen-substituted dibenzoylmethanes were active. These results demonstrate that dibenzoylmethanes can inhibit the mutagenicity of 2-nitrofluorene, and that modifications made on the benzene rings of dibenzoylmethane cannot enhance the antimutagenicity of this parent compound.