1426-55-7

Basic information

• Product Name: (4-Fluorophenyl)(4-Methoxyphenyl)Methanol
• Synonyms: (4-Fluorophenyl)(4-Methoxyphenyl)Methanol
• CAS NO: 1426-55-7
• Molecular Formula: C₁₄H₁₃FO₂
• Molecular Weight: 232.2502232
• Mol File: 1426-55-7.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 363.9±37.0 °C(Predicted)
• Appearance: /
• Density: 1.189±0.06 g/cm3(Predicted)
• PKA: 13.55±0.20(Predicted)
• CAS DataBase Reference: (4-Fluorophenyl)(4-Methoxyphenyl)Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Fluorophenyl)(4-Methoxyphenyl)Methanol(1426-55-7)
• EPA Substance Registry System: (4-Fluorophenyl)(4-Methoxyphenyl)Methanol(1426-55-7)

Safety Data

• Hazardous Substances Data: 1426-55-7(Hazardous Substances Data)

Usage

Description

(4-Fluorophenyl)(4-Methoxyphenyl)Methanol, also known as FPMMP, is a chemical compound that features a methanol moiety with a fluoroand a methoxy-substituted phenyl group. It is widely recognized as a building block in the synthesis of a variety of organic compounds, predominantly in the pharmaceutical and agrochemical sectors.

Uses

Used in Pharmaceutical Industry:
FPMMP is utilized as an intermediate in the synthesis of pharmaceuticals due to its potential biological activities, such as anti-inflammatory and analgesic properties. Its unique structure allows it to be a valuable component in drug discovery and development, contributing to the creation of novel medications.
Used in Agrochemical Industry:
In the agrochemical field, FPMMP serves as a key building block for the synthesis of various agrochemicals. Its role in this industry is instrumental in developing new compounds that can improve crop protection and yield.
Used in Organic Chemistry Research:
FPMMP may also act as a precursor for the preparation of other functionalized molecules, expanding its utility in organic chemistry research. This application supports the advancement of chemical science and the discovery of new materials and compounds with diverse applications.
It is important to follow proper safety measures and handling protocols when working with FPMMP to ensure the safety of individuals and the environment.

Upstream product

• 345-89-1 4-fluoro-4'-methoxybenzophenone 
• 459-57-4 4-fluorobenzaldehyde 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 123-11-5 4-methoxy-benzaldehyde 
• 352-13-6 4-flourophenylmagnesium bromide 
• 1765-93-1 4-fluoroboronic acid 
• 5720-07-0 4-methoxyphenylboronic acid 
• 104-92-7 1-bromo-4-methoxy-benzene 

Downstream Products

• 3862-51-9 2-Nitro-2-(4'-fluor-4-methoxy-benzhydryl)-indandion-(1,3) 
• 38695-26-0 1-(4-fluorobenzyl)-4-methoxybenzene 
• 1842-03-1 C₁₄H₁₂ClFO 
• 39769-54-5 C₁₄H₁₂FO⁽¹⁺⁾ 
• 64583-40-0 C₁₄H₁₂BrFO 
• 96835-15-3 1-((4-fluorophenyl)(4-methoxyphenyl)methyl)piperidine 
• 1069111-71-2 2-(4-fluorophenyl)-2-(4-methoxyphenyl)acetonitrile 
• 1332707-98-8 1-((4-fluorophenyl)((4-fluorophenyl)(4-methoxyphenyl)methoxy)methyl)-4-methoxybenzene 

Relevant articles and documents

Continuous Flow Acylation of (Hetero)aryllithiums with Polyfunctional N,N-Dimethylamides and Tetramethylurea in Toluene

The continuous flow reaction of various aryl or heteroaryl bromides in toluene in the presence of THF (1.0 equiv) with sec-BuLi (1.1 equiv) provided at 25 °C within 40 sec the corresponding aryllithiums which were acylated with various functionalized N,N-

Scandium as a pre-catalyst for the deoxygenative allylation of benzylic alcohols

Scandium triflate is an effective pre-catalyst for the deoxygenative allylation of benzylic alcohols with a narrow substrate window. The reaction is shown to proceed through a "hidden Br?nsted acid" mechanism. The reaction is efficient provided that the aryl group is neither too electron rich nor too electron poor. It is shown that this allows useful selectivity. The reaction also works for benzyhydryl alcohols with broader scope. The reaction may also be catalysed by Nafion.

Sodium bisulfite: An efficient catalyst for ether formation via dehydration of aromatic/aliphatic alcohol

Straightforward etherification of benzyl alcohols (1) via intermolecular dehydration can be efficiently catalyzed by sodium bisulfite under solvent-free conditions. In the presence of 0.3 mol% or 0.6 mol% amount of sodium bisulfite, symmetric and unsymmetric ethers are prepared from the corresponding alcohols in high yields (up to 95%). Etherification of benzhydryl alcohols is also discussed. Copyright