1427262-60-9

Basic information

• Product Name: 2-(5-benzyl-1,3,4-oxadiazol-2-yl)-6-bromo-5-(trifluoromethyl)pyridin-3-amine
• Synonyms: 2-(5-benzyl-1,3,4-oxadiazol-2-yl)-6-bromo-5-(trifluoromethyl)pyridin-3-amine
• CAS NO: 1427262-60-9
• Molecular Weight: 399.17
• Mol File: 1427262-60-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(5-benzyl-1,3,4-oxadiazol-2-yl)-6-bromo-5-(trifluoromethyl)pyridin-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-benzyl-1,3,4-oxadiazol-2-yl)-6-bromo-5-(trifluoromethyl)pyridin-3-amine(1427262-60-9)
• EPA Substance Registry System: 2-(5-benzyl-1,3,4-oxadiazol-2-yl)-6-bromo-5-(trifluoromethyl)pyridin-3-amine(1427262-60-9)

Safety Data

• Hazardous Substances Data: 1427262-60-9(Hazardous Substances Data)

Upstream product

• 1427262-62-1 3-amino-6-bromo-5-(trifluoromethyl)picolinohydrazide 
• 866775-17-9 3-amino-5-trifluoromethyl-pyridine-2-carboxylic acid methyl ester 
• 866775-16-8 3-nitro-5-trifluoromethyl-pyridine-2-carbonitrile 
• 33252-64-1 3-nitro-5-trifluoromethylpyridin-2-ol 
• 1214336-90-9 3-amino-6-(2,6-difluorophenyl)-5-trifluoromethyl-2-pyridinecarboxylicacid 
• 1427262-61-0 3-amino-6-bromo-N'-(2-phenylacetyl)-5-(trifluoromethyl)picolinohydrazide 
• 866775-18-0 3-amino-6-bromo-5-trifluoromethyl-pyridine-2-carboxylic acid methyl ester 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF CYSTIC FIBROSIS

The present invention provides pyridin-oxadiazole/thiadiazole derivatives of Formula I wherein A is N or CR 4a; and (ii) or (iii) which restore or enhance the function of mutant and/or wild type CFTR to treat cystic fibrosis, primary ciliary dyskinesia, chronic bronchitis, chronic obstructive pulmonary disease, asthma, respiratory tract infections, lung carcinoma, xerostomia and keratoconjunctivitis sire, or constipation (IBS, IBD, opioid induced). Pharmaceutical compositions comprising such derivatives are also encompassed.