142758-96-1

Basic information

• Product Name: (4S)-4-(cyclohexylmethyl)-2-oxazolidinone
• Synonyms: (4S)-4-(cyclohexylmethyl)-2-oxazolidinone
• CAS NO: 142758-96-1
• Molecular Weight: 183.25
• Mol File: 142758-96-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4S)-4-(cyclohexylmethyl)-2-oxazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-4-(cyclohexylmethyl)-2-oxazolidinone(142758-96-1)
• EPA Substance Registry System: (4S)-4-(cyclohexylmethyl)-2-oxazolidinone(142758-96-1)

Safety Data

• Hazardous Substances Data: 142758-96-1(Hazardous Substances Data)

Upstream product

• 35166-78-0 cyclohexylmethyl magnesium bromide 
• 124-38-9 carbon dioxide 
• 131288-67-0 (2S)-2-amino-3-cyclohexyl-1-propanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 103322-56-1 tert-butyl [(1S)-2-cyclohexyl-1-(hydroxymethyl)ethyl]carbamate 
• 142673-27-6 4-Cyclohexylmethyl-oxazolidin-2-one 

Downstream Products

• 112530-20-8 (4S)-3-((2'R)-2'-methylbutanoyl)-4-(cyclohexylmethyl)-2-oxazolidinone 
• 112530-19-5 (4S)-3-((2'S)-2'-methylbutanoyl)-4-(cyclohexylmethyl)-2-oxazolidinone 

Relevant articles and documents

Synthesis of chiral oxazolidin-2-ones by 1,2-amino alcohols, carbon dioxide and electrogenerated acetonitrile anion

An improved electrochemical synthesis of chiral oxazolidin-2-ones from chiral 1,2-amino alcohols is obtained by direct electrolysis of solutions of MeCN-TEAP containing the amino alcohol, with subsequent CO2 bubbling and addition of TsCl. This

Practical Preparation of Chiral 4-Substituted 2-Oxazolidinones

A versatile and practical route to both enantiomers of a wide variety of 4-substituted 2-oxazolidinones from the parent heterocycle is provided by regioselective substitutions via 4-methoxy derivative followed by chromatographic separation of the diastereomers derived from N-2-exo-methoxy-1-apocamphanecarbonylation.