142885-92-5 Usage
Description
5-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]thio]-1H-benziMidazole N-Oxide is a chemical compound derived from Omeprazole, a proton pump inhibitor commonly used as an antiulcerative agent. 5-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]thio]-1H-benziMidazole N-Oxide possesses a complex molecular structure with various functional groups, including methoxy, methyl, and thiol groups, which contribute to its potential applications in different fields.
Uses
Used in Pharmaceutical Industry:
5-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]thio]-1H-benziMidazole N-Oxide is used as a metabolite of Omeprazole for the treatment of various ulcerative conditions. Its role in the metabolism of Omeprazole contributes to the drug's efficacy in reducing gastric acid production, thereby alleviating symptoms and promoting healing of ulcers.
Used in Research and Development:
5-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]thio]-1H-benziMidazole N-Oxide can be utilized in research and development for the study of proton pump inhibitors and their metabolites. Understanding the properties and interactions of 5-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]thio]-1H-benziMidazole N-Oxide can provide insights into the mechanisms of action of Omeprazole and potentially lead to the development of new antiulcerative agents or other therapeutic applications.
Used in Drug Metabolism Studies:
5-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]thio]-1H-benziMidazole N-Oxide serves as a valuable compound for studying drug metabolism pathways. By examining how this compound is processed and eliminated from the body, researchers can gain a better understanding of the metabolic processes involved in the breakdown and clearance of proton pump inhibitors and other related drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 142885-92-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,8,8 and 5 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 142885-92:
(8*1)+(7*4)+(6*2)+(5*8)+(4*8)+(3*5)+(2*9)+(1*2)=155
155 % 10 = 5
So 142885-92-5 is a valid CAS Registry Number.
142885-92-5Relevant articles and documents
Efficient synthesis of N-Oxide derivatives: Substituted 2-(2-(pyridyl-N-oxide)methylsulphinyl)benzimidazoles
Ray, Purna C.,Mittapelli, Vasantha,Rohatgi, Amit,Tyagi, Om Dutt
, p. 2861 - 2868 (2007)
Different substituted 2-chloromethylpyridyl derivatives (6a-d) were oxidized with mCPBA to give the respective 2-chloromethylpyridine-N-oxide derivatives (7a-d) at low temperature, which on condensation with 2-mercapto-1H-benzimidazole (8a-c) in the presence of aprotic solvents give the 2-[[(pyridin-2-yl-1-oxide)methyl]sulfanyl]-1H-benzimidazole (9a-d) in good yield. Finally, 9a-d oxidized with mCPBA in chlorinated solvent gives a mixture of 2-[[(pyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole (3a-d, 10%) and 2-[[(pyridin-2-yl-1-oxide) methyl]sulfinyl]-1H-benzimidazole (4a-d, 90%) derivatives. Copyright Taylor & Francis Group, LLC.
