14293-14-2Relevant articles and documents
ESTROGEN MODULATORS
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Page/Page column 59, (2008/06/13)
The present application is directed to a new class of isoxazoles and their use as estrogen modulators.
Studies in Potential Antifertility Agents: Part XXIV - Synthesis of 2,3-Disubstituted 4'-(&β-dialkylaminoethoxy)propiophenones
Rao, K. V. B.,Iyer, R. N.
, p. 54 - 58 (2007/10/02)
A number of 2,3-disubstituted 4'-(β-dialkylaminoethoxy)propiophenones (32-41) have been synthesized as the structural analogs of a potent antifertility agent erythro-2,3-diphenyl-4'-(β-pyrrolidinoethoxy)valerophenone (1).Compounds 34, 35, 38 and 40 show cent per cent activity at dose levels of 2.5, 10, 10, 10 and 1 mg/kg, respectively.The structure activity relationship has also been discussed.