143-16-8 Usage
Description
DI-N-HEXYLAMINE, also known as Dihexylamine, is a clear colorless liquid with chemical properties that make it suitable for various applications in different industries. It is primarily used in organic syntheses and is involved in the preparation of succinic acid.
Uses
Used in Organic Synthesis:
DI-N-HEXYLAMINE is used as a reagent in the field of organic synthesis for its ability to facilitate various chemical reactions and contribute to the formation of desired products.
Used in Chemical Industry:
DI-N-HEXYLAMINE is used as a catalyst in the chemical industry, particularly in the production of succinic acid, which is an important building block for various chemicals and materials.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, DI-N-HEXYLAMINE could potentially be used in the pharmaceutical industry as an intermediate in the synthesis of various drugs and pharmaceutical compounds due to its role in organic synthesis.
Air & Water Reactions
DI-N-HEXYLAMINE may be sensitive to prolonged exposure to air. Insoluble in water.
Reactivity Profile
DI-N-HEXYLAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Health Hazard
ACUTE/CHRONIC HAZARDS: DI-N-HEXYLAMINE is readily absorbed through the skin.
Fire Hazard
DI-N-HEXYLAMINE is combustible.
Safety Profile
poison by ingestion,
skin contact, and intravenous routes. A skin
exposed to heat or flame; can react with
oxidizing materials. To fight fire, use CO2,
dry chemical. When heated to
decomposition it emits toxic fumes of NOx. See also AMINES.
Check Digit Verification of cas no
The CAS Registry Mumber 143-16-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,4 and 3 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 143-16:
(5*1)+(4*4)+(3*3)+(2*1)+(1*6)=38
38 % 10 = 8
So 143-16-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H27N/c1-3-5-7-9-11-13-12-10-8-6-4-2/h13H,3-12H2,1-2H3/p+1
143-16-8Relevant articles and documents
Hydroaminomethylation of olefins using a rhodium carbene catalyst
Seayad, Abdul Majeed,Selvakumar, Kumaravel,Ahmed, Moballigh,Beller, Matthias
, p. 1679 - 1683 (2003)
Hydroaminomethylation of terminal as well as internal aliphatic and aromatic olefins with various amines is described in the presence of [Rh(cod)(Imes)Cl] as a catalyst. In general good to excellent yields and high chemoselectivity were obtained in THF at 85-105°C using 0.1 mol% of catalyst.
CO2-tuned highly selective reduction of formamides to the corresponding methylamines
Chao, Jianbin,Guo, Zhiqiang,Pang, Tengfei,Wei, Xuehong,Xi, Chanjuan,Yan, Leilei
supporting information, p. 7534 - 7538 (2021/10/12)
We herein describe an efficient, CO2-tuned and highly selective C-O bond cleavage of N-methylated formanilides. With easy-to-handle and commercially available NaBH4 as the reductant, a variety of formanilides could be turned into the desired tertiary amines in moderate to excellent yields. The role of CO2 has been investigated in detail, and the mechanism is proposed on the basis of experiments.
Amination of aliphatic alcohols with urea catalyzed by ruthenium complexes: effect of supporting ligands
Dindar, Sara,Nemati Kharat, Ali
, (2020/09/02)
In the present study, ruthenium-catalyzed amination of alcohols by urea as a convenient ammonia carrier in the presence of free diphosphine ligands has been described. A number of ruthenium-phosphine complexes have been studied among which, [(Cp)RuCl(dppe)] was found as an efficient catalyst for alcohol amination reaction. The crystal structures of two new half-sandwich ruthenium complexes, [(Cp)RuCl(dppe)] and [(C6H6)RuCl2(PHEt2)], were determined by X-ray crystallographic analysis. Also the effect of using different supporting phosphines, ratio of raw materials and reaction temperature on conversion and selectivity was investigated. Under optimum reaction conditions high conversion (98percent) and chemo-selectivity toward secondary amines were obtained.
