143105-05-9Relevant articles and documents
Aromatic Heteroannulation via Metalation-Cyclization of N-Acyl-2-chlorobenzenesulfonamides and N-Acylbenzenesulfonamides
Hermann, Christine K. F.,Campbell, James A.,Greenwood, Thomas D.,Lewis, Judith A.,Wolfe, James F.
, p. 5328 - 5334 (2007/10/02)
N-Acyl-2-chlorobenzenesulfonamides 7a-d undergo competitive metal-halogen exchange and ortho-deprotonation or α-deprotonation reactions when treated sequentially with sodium hydride and n-butyllithium.The o-lithio intermediates derived from metal-halogen