143211-11-4Relevant articles and documents
Preparation method of 2-(2-methylphenoxy methyl) benzoyl nitrile
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Paragraph 0007; 0030-0062, (2021/01/30)
The invention relates to a preparation method of 2-(2-methylphenoxy methyl) benzoyl nitrile, and belongs to the technical field of organic synthesis. According to the method, 2- (-2methyl phenoxy) methylene benzoyl chloride and sodium cyanide are used as reaction raw materials, and the 2-(2-methylphenoxy methyl) benzoyl nitrile can be directly synthesized by using a micro-channel reactor. By utilizing the synthesis method disclosed by the invention, the reaction yield can be increased to 95% or above, the dosage of highly toxic chemical sodium cyanide can be effectively reduced, and the safetyof the synthesis process is improved. The preparation method has the advantages that the production process is simple, continuous production can be achieved, the reaction time is short, and generatedwaste is less than that of an existing synthesis process.
Preparation method of 2-(2-methyl phenoxyl)-methylene benzoyl cyanide
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Paragraph 0027; 0028; 0029; 0030; 0031; 0032; 0033-0036, (2017/09/01)
The invention relates to the field of chemical synthesis and in particular discloses a preparation method of 2-(2-methyl phenoxyl)-methylene benzoyl cyanide. The preparation method takes potassium ferrocyanide as a cyaniding agent, and preparation with 2-(2-methyl phenoxyl)-methylene benzoyl cyanide is carried out, so that the target product 2-(2-methyl phenoxyl)-methylene benzoyl cyanide can be obtained. Compared with the prior art, the preparation method disclosed by the invention has the advantages that potassium ferrocyanide is adopted as the cyaniding agent, so that the price is low, and the 2-(2-methyl phenoxyl)-methylene benzoyl cyanide is nontoxic and harmless; meanwhile, the ultimate reaction yield reaches more than 90%, and the reaction is safer; besides, the raw material cost is low, the technology is simple, the operation is convenient, and good conditions are provided for industrial production.
AN IMPROVED PROCESS FOR THE SYNTHESIS OF STROBILURIN FUNGICIDES VIZ TRIFLOXYSTROBIN AND KRESOXIM-METHYL
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Page/Page column 28; 35, (2013/10/21)
The present invention relates to an improved process for the synthesis of E-isomer of compound of formula (5). It further relates to the conversion of formula (5), wherein R is H, to Intermediate (I) and subsequently to substantially pure Trifloxystrobin, compound of formula (I) in good yield.