143216-63-1Relevant articles and documents
Stereoselective synthesis of the 1,N2-deoxyguanosine adducts of cinnamaldehyde. A stereocontrolled route to deoxyguanosine adducts of α,β-unsaturated aldehydes
Rezaei, Mansoureh,Harris, Thomas M.,Rizzo, Carmelo J.
, p. 7513 - 7516 (2007/10/03)
α,β-Unsaturated aldehydes (enals) react with deoxyguanosine and have mutagenic potential. For higher enals, the reaction of deoxyguanosine gives diastereomeric 6-substituted 8-hydroxypyrimidopurinone products. These stereoisomers may have different local
Chiral α,β-Epoxy Group as a Stereocontrolling Element in the Reduction of N-Metalloimines. A Short Synthesis of anti-Epoxy Amines
Urabe, Hirokazu,Aoyama, Yoshiaki,Sato, Fumie
, p. 5056 - 5057 (2007/10/02)
Reduction of the α,β-epoxy N-metalloimines generated from the TBS ether of (2S,3S)-3-cyano-2,3-epoxy-1-propanol (1), Grignard reagents, and Me3SiCl with NaBH4 afforded the TBS ethers of (2S,3S,4S)-4-amino-2,3-epoxy-1-alkanols 4 with diastereoselectivities of up to 95:5.