143317-15-1Relevant articles and documents
Synthesis and reactions of Biginelli compounds -5. Facile preparation and resolution of a stable 5-dihydropyrimidinecarboxylic acid
Kappe, C. Oliver,Uray, Georg,Roschger, Peter,Lindner, Wolfgang,Kratky, Christoph,Keller, Walter
, p. 5473 - 5480 (1992)
The synthesis of enantiomerically pure 5-dihydropyrimidinecarboxylic acids 7a,b is described. Condensation of benzyl acetoacetate with methylurea and 2-naphthaldehyde gave Biginelli compound 3b, which after methylation and removal of the benzyl group led