143370-20-1

Basic information

• Product Name: 6-(2-acetyl-4-methoxy-phenylamino)quinoline-5,8-dione
• Synonyms: 6-(2-acetyl-4-methoxy-phenylamino)quinoline-5,8-dione
• CAS NO: 143370-20-1
• Molecular Weight: 322.32
• Mol File: 143370-20-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 6-(2-acetyl-4-methoxy-phenylamino)quinoline-5,8-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(2-acetyl-4-methoxy-phenylamino)quinoline-5,8-dione(143370-20-1)
• EPA Substance Registry System: 6-(2-acetyl-4-methoxy-phenylamino)quinoline-5,8-dione(143370-20-1)

Safety Data

• Hazardous Substances Data: 143370-20-1(Hazardous Substances Data)

Upstream product

• 54232-20-1 6-methoxy-5,8-quinolinedione 
• 23042-77-5 1-(2-amino-5-methoxy-phenyl)-ethanone 
• 10470-83-4 5,8-quinolinedione 

Downstream Products

• 143370-23-4 neocalliactine methyl ether 
• 143370-23-4 5-methoxyascididemin 

Relevant articles and documents

TOTAL SYNTHESIS OF KUANONIAMINE A, 11-HYDROXYASCIDIDEMIN, AND NEOCALLIACTINE ACETATE

A pentacyclic aromatic alkaloid, kuanoniamine A (5) was synthesized from 6-methoxybenzothiazole-4,7-dione (7) and 2-aminoacetophenone (8).Similarly, 11-hydroxyascididemin (4) was prepared from 6-bromo-4-chloro-5,8-dimethoxyquinoline (12).The structure of neocalliactine acetate, a derivative of calliactine, was determined as 19 by total synthesis from 6-methoxy-5,8-quinolinedione (23) and 2-amino-5-methoxyacetophenone (24).

Synthetic studies on pentacyclic aromatic alkaloids, kuanoniamine A, 11-hydroxyascididemin, and neocalliactine acetate

A pentacyclic aromatic alkaloid, kuanoniamine A (6) was synthesized in three steps from 6-methoxybenzothiazole-4,7-dione (8) and 2-aminoacetophenone (9). 11-Hydroxyascididemin (4) was prepared from 5,8-quinolinedione (13, 14) or 1,4-acridinedione (20). The structure of neocalliactine acetate, a derivative of calliactine, was determined to be 5 by total synthesis from 6-methoxy-5,8-quinolinedione (28) and 2-amino-5-methoxyacetophenone (29).