143390-87-8 Usage
Description
(E)-9-[[5-(3,3-Dimethyloxiranyl)-3-methyl-2-pentenyl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one is a complex organic molecule characterized by a unique structure that features a fused furan and benzopyran ring system. (E)-9-[[5-(3,3-Dimethyloxiranyl)-3-methyl-2-pentenyl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one is notable for its pentenyl and oxiranyl groups, as well as a ketone functional group. The intricate arrangement of these components suggests potential pharmaceutical or biological activity, as similar structures have been linked to anticancer, anti-inflammatory, and antioxidant properties. Further research is necessary to explore the pharmacological potential and safety profile of this compound for possible drug development or other applications.
Uses
Used in Pharmaceutical Industry:
(E)-9-[[5-(3,3-Dimethyloxiranyl)-3-methyl-2-pentenyl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one is used as a potential candidate for drug development due to its complex chemical structure and the presence of biologically active groups. (E)-9-[[5-(3,3-Dimethyloxiranyl)-3-methyl-2-pentenyl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one's potential pharmaceutical applications are attributed to the similar properties observed in related structures, such as anticancer, anti-inflammatory, and antioxidant activities.
Used in Research and Development:
In the field of scientific research, (E)-9-[[5-(3,3-Dimethyloxiranyl)-3-methyl-2-pentenyl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one serves as a valuable subject for exploring the relationship between chemical structure and biological activity. Its unique composition may provide insights into the development of new therapeutic strategies and contribute to the advancement of pharmaceutical sciences.
Used in Chemical Synthesis:
(E)-9-[[5-(3,3-Dimethyloxiranyl)-3-methyl-2-pentenyl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one can be utilized as a key intermediate or building block in the synthesis of more complex molecules with tailored properties. Its unique structure and functional groups make it a promising candidate for the development of novel compounds with specific applications in various industries, including pharmaceuticals, materials science, and agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 143390-87-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,3,9 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 143390-87:
(8*1)+(7*4)+(6*3)+(5*3)+(4*9)+(3*0)+(2*8)+(1*7)=128
128 % 10 = 8
So 143390-87-8 is a valid CAS Registry Number.
143390-87-8Relevant articles and documents
Synthesis of 8-geranyloxypsoralen analogues and their evaluation as inhibitors of CYP3A4
Row,Brown,Stachulski,Lennard
, p. 3865 - 3871 (2007/10/03)
Furanocoumarins have been shown to inhibit CYP3A4 in vitro with varying degrees of potency [Pharmacogenetics 1997, 7, 391-396; Chem. Res. Toxicol. 1998, 11, 252-259; Drug Metab. Dispos. 1997, 25, 1228-1233; Br. J. Pharmacol. 2000, 130, 1369-1377]. In this study, we report the effects of a series of novel furanocoumarins based on the naturally occurring derivative 8-geranylepoxypsoralen which has been shown to be a more potent inhibitor of CYP3A4 than its 5-position-substituted counterpart bergamottin [Drug Metab. Dispos. 2000, 28, 766-771; Jpn. J. Pharmacol. 2000, 82, 122-129]. Compounds were designed, synthesised and tested for their ability to inhibit CYP3A4 activity in human liver microsomes using testosterone as the marker substrate. Both the saturated and unsaturated phenolic furanocoumarin derivatives were found to be inactive. However, the 8-alkyloxy-furanocoumarin analogues were shown to inhibit CYP3A4 activity in a dose dependent manner, with IC50 values ranging from 0.78 ± 0.11 to 3.93 ± 0.53 μM. The reduced furan derivative dihydro-8-geranyloxypsoralen showed a 4-fold decrease in inhibitory potency, suggesting that the furan moiety plays a role in the interaction between these compounds and CYP3A4.