14351-29-2

Basic information

• Product Name: dammarenediol
• Synonyms: dammarenediol;(20S)-5α-Dammara-24-ene-3β,20-diol;5α-Dammar-24-ene-3β,20-diol;Dammarenediol II
• CAS NO: 14351-29-2
• Molecular Formula: C30H52O2
• Molecular Weight: 444.7327
• Mol File: 14351-29-2.mol
• Article Data: 10

Chemical Properties

• Melting Point: 130-133 °C
• Boiling Point: 529.4 °C at 760 mmHg
• Flash Point: 212 °C
• Appearance: /
• Density: 0.993 g/cm³
• Vapor Pressure: 2.02E-13mmHg at 25°C
• Refractive Index: 1.517
• PKA: 15.06±0.29(Predicted)
• CAS DataBase Reference: dammarenediol(CAS DataBase Reference)
• NIST Chemistry Reference: dammarenediol(14351-29-2)
• EPA Substance Registry System: dammarenediol(14351-29-2)

Safety Data

• Hazardous Substances Data: 14351-29-2(Hazardous Substances Data)

Usage

Description

Dammarenediol is a tetracyclic triterpenoid belonging to the dammarane family. It is characterized by the presence of a double bond between positions 24 and 25, and is substituted by hydroxy groups at the 3betaand 20positions. This unique structure endows dammarenediol with various biological activities and potential applications in different industries.

Uses

Used in Pharmaceutical Industry:
Dammarenediol is used as a pharmaceutical compound for its potential therapeutic properties. The expression is: dammarenediol is used as a therapeutic agent for its biological activities, which may include anti-inflammatory, anti-cancer, and immunomodulatory effects.
Used in Cosmetic Industry:
In the cosmetic industry, dammarenediol is used as an active ingredient for its potential benefits in skincare. The expression is: dammarenediol is used as a skincare ingredient for its potential anti-aging, moisturizing, and protective properties.
Used in Traditional Medicine:
Dammarenediol is also utilized in traditional medicine, particularly in the preparation of herbal remedies. The expression is: dammarenediol is used as a component in traditional medicine for its potential healing and therapeutic effects.
Used in Drug Delivery Systems:
Similar to gallotannin, dammarenediol can be employed in drug delivery systems to enhance its bioavailability and therapeutic outcomes. The expression is: dammarenediol is used as a component in drug delivery systems for its potential to improve the delivery and efficacy of various pharmaceutical compounds.

InChI:InChI=1/C30H52O2/c1-20(2)10-9-16-30(8,32)22-13-18-28(6)21(22)11-12-24-27(5)17-15-25(31)26(3,4)23(27)14-19-29(24,28)7/h10,21-25,31-32H,9,11-19H2,1-8H3/t21?,22?,23-,24+,25-,27-,28+,29+,30-/m0/s1

Upstream product

• 471-69-2 dipterocarpol 
• 37586-57-5 4-methyl-3-pentenylmagnesium bromide 
• 181776-84-1 (1S,4aR,4bR,7S,8aR,10aR)-7-Hydroxy-1,4b,8,8,10a-pentamethyl-1-(4-oxo-pentyl)-dodecahydro-phenanthren-2-one 
• 181776-86-3 Phenyl-carbamic acid (3S,5R,8R,9R,10R,14S)-17-acetyl-4,4,8,10,14-pentamethyl-2,3,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 
• 181776-90-9 Phenyl-carbamic acid (2S,4aR,4bR,8S,8aR,10aR)-1,1,4a,8,8a-pentamethyl-7-oxo-8-(4-oxo-pentyl)-tetradecahydro-phenanthren-2-yl ester 
• 181776-88-5 Phenyl-carbamic acid (3S,5R,8R,9R,10R,13R,14R,17S)-17-acetyl-4,4,8,10,14-pentamethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester 
• 128685-91-6 (R)-2-[(3S,5R,9S,10R,13S,14S,17R)-3-(tert-Butyl-dimethyl-silanyloxy)-4,4,8,10,14-pentamethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-6-methyl-hept-5-en-2-ol 
• 1193-55-1 2-methylcyclohexane-1,3-dione 
• 128685-58-5 6-(2-ethyl-[1,3]dioxolan-2-yl)-hex-1-en-3-one 
• 17745-32-3 methyl 5-oxoheptanoate 
• 128685-74-5 6-(2-ethyl-[1,3]dioxolan-2-yl)-hex-1-en-3-ol 
• 128685-73-4 4-(2-Ethyl-[1,3]dioxolan-2-yl)-butyraldehyde 
• 128685-72-3 4-(2-Ethyl-[1,3]dioxolan-2-yl)-butyric acid methyl ester 
• 128685-81-4 C₂₃H₃₆O₃ 

Downstream Products

• 927799-52-8 C₃₈H₅₆O₅ 

Related news

Characterization of a dammarenediol (cas 14351-29-2) synthase in Centella asiatica (L.) Urban08/04/2019

To elucidate the exact function of CabAS in Centella asiatica, which was previously reported as a putative β-amyrin synthase [Plant Cell Rep, 24:304–311, 2005], this gene was functionally expressed in the lanosterol synthase-deficient yeast mutant (erg7). After inducing the CabAS gene with gal...detailed

Relevant articles and documents

The fluorine atom as a cation-stabilizing auxiliary in biomimetic polyene cyclizations: Total synthesis of dl-dammarenediol

Dammarenediols I (1a) and II (1b) were prepared by an efficient nonenzymatic biomimetic polyene tetracyclization route. The cyclization substrate, pentaenol 3, contains a tetramethylallylic alcohol initiator, an allyltrimethylsilane terminating group, and

Synthesis and Cytotoxicity of Derivatives of Dipterocarpol, a Metabolite of Dipterocarpus alatus

New derivatives with hydroxy, epoxy, hydroxyimino, acetoxy, lactol, methoxylactol, and indole groups in ring A and the side chain were synthesized via chemical transformations of dipterocarpol. The structure- cytotoxicity relationship was described for the dipterocarpol derivatives.

Polymeric derivatives of dipterocarpol, a dammarane triterpenoid

Polymeric derivatives of dammarane triterpenoids with both labile and strong (covalent) polymer-triterpenoid bonds were prepared from N-vinylpyrrolidone copolymers. Pleiades Publishing, Inc., 2006.