143585-49-3

Basic information

• Product Name: (1R,2R)-N,N'-bis(2,4,6-triisopropylbenzenesulfonyl)-cyclohexane-1,2-diamine
• Synonyms: (1R,2R)-N,N'-bis(2,4,6-triisopropylbenzenesulfonyl)-cyclohexane-1,2-diamine
• CAS NO: 143585-49-3
• Molecular Weight: 647
• Mol File: 143585-49-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (1R,2R)-N,N'-bis(2,4,6-triisopropylbenzenesulfonyl)-cyclohexane-1,2-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R)-N,N'-bis(2,4,6-triisopropylbenzenesulfonyl)-cyclohexane-1,2-diamine(143585-49-3)
• EPA Substance Registry System: (1R,2R)-N,N'-bis(2,4,6-triisopropylbenzenesulfonyl)-cyclohexane-1,2-diamine(143585-49-3)

Safety Data

• Hazardous Substances Data: 143585-49-3(Hazardous Substances Data)

Upstream product

• 63877-57-6 2,4,6-tri(iso-propyl)benzenesulfonic acid 
• 20439-47-8 (1R,2R)-1,2-diaminocyclohexane 
• 591-87-7 Allyl acetate 
• 6553-96-4 2,4,6-triisopropylphenylsulfonyl chloride 

Relevant articles and documents

MgBr2-promoted enantioselectIVe aryl addition of ArTi(OiPr)3 to ketones catalyzed by a titanium(IV) catalyst of N,N′-sulfonylated (1R,2R)-cyclohexane-1,2-diamine

MgBr2-promoted asymmetric addition of ArTi(OiPr)3 to ketones catalyzed by a titanium catalyst of N,N′-sulfonylated (1R,2R)-cyclohexane-1,2-diamines is reported, and results showed that the chiral N,N′-sulfonylated cyclohex

Catalytic asymmetric synthesis of vicinal diamine derivatives through enantioselective N-allylation using chiral π-allyl Pd-catalyst

(Chemical Equation Presented) N-Monoallylation of meso-vicinal diamine bistrisylamides using a chiral π-allyl-Pd catalyst proceeded in an enantioselective manner (up to 90% ee) to give desymmetrization products in good yields. The product was converted to the known σ-receptor agonist in short steps. In addition, the present catalytic asymmetric N-allylation was applied to kinetic resolution of racemic-diamide.

A Catalytic Enantioselective Reaction Using a C2-Symmetric Disulfonamide as a Chiral Ligand: Alkylation of Aldehydes Catalyzed by Disulfonamide-Ti(O-i-Pr)4-Dialkyl Zinc System

Excellent enantioselective alkylation of aldehydes with dialkylzinc has been developed.This methodology is based on the concept of modifying the Lewis acid with a C2-symmetric, electron-withdrawing disulfonamide.The chiral Lewis acid catalysts used in the present study are the titanium complexes, prepared in-situ from disulfonamide and Ti(O-i-Pr)4.Key Words: Chiral disulfonamide; chiral titanium complex; enantioselective alkylation; dialkyl zinc; catalytic reaction