1436383-97-9

Basic information

• Product Name: 3-bromo-2-methyl-N-[(3-methylsulfonylphenyl)methyl]imidazo[1,2-a]pyrazin-8-amine
• Synonyms: 3-bromo-2-methyl-N-[(3-methylsulfonylphenyl)methyl]imidazo[1,2-a]pyrazin-8-amine
• CAS NO: 1436383-97-9
• Molecular Weight: 395.28
• Mol File: 1436383-97-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-bromo-2-methyl-N-[(3-methylsulfonylphenyl)methyl]imidazo[1,2-a]pyrazin-8-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-2-methyl-N-[(3-methylsulfonylphenyl)methyl]imidazo[1,2-a]pyrazin-8-amine(1436383-97-9)
• EPA Substance Registry System: 3-bromo-2-methyl-N-[(3-methylsulfonylphenyl)methyl]imidazo[1,2-a]pyrazin-8-amine(1436383-97-9)

Safety Data

• Hazardous Substances Data: 1436383-97-9(Hazardous Substances Data)

Upstream product

• 1124321-36-3 3-bromo-8-chloro-2-methyl-imidazo[1,2-a]pyrazine 
• 771573-22-9 1-[3-(methylsulfonyl)phenyl]methanamine 
• 85333-43-3 8-chloro-2-methyl-imidazo[1,2-a]pyrazine 

Downstream Products

• 1124321-01-2 4-[2-methyl-8-[(3-methylsulfonylphenyl)methylamino]imidazo[1,2-a]pyrazin-3-yl]phenol 
• 1436383-95-7 2-fluoro-4-[2-methyl-8-[(3-methylsulfonylphenyl)methylamino]imidazo[1,2-a]pyrazin-3-yl]phenol 

Relevant articles and documents

Identification of a series of compounds with potent antiviral activity for the treatment of enterovirus infections

Rhinovirus (genus enterovirus) infections are responsible for many of the severe exacerbations of asthma and chronic obstructive pulmonary disease. Other members of the genus can cause life-threatening acute neurological infections. There is currently no antiviral drug approved for the treatment of such infections. We have identified a series of potent, broad-spectrum antiviral compounds that inhibit the replication of the human rhinovirus, Coxsackie virus, poliovirus, and enterovirus-71. The mechanism of action of the compounds has been established as inhibition of a lipid kinase, PI4KIIIβ. Inhibition of hepatitis C replication in a replicon assay correlated with enterovirus inhibition.