143700-04-3 Usage
Description
(R)-tert-butyl 3-azidopyrrolidine-1-carboxylate is a chemical compound belonging to the class of azidopyrrolidine carboxylates. It is a derivative of pyrrolidine, featuring a five-membered ring with one nitrogen atom, a tert-butyl group attached to the nitrogen, and an azide group (N3) on the third carbon atom. (R)-tert-butyl 3-azidopyrrolidine-1-carboxylate has been investigated for its potential in organic synthesis and as a building block for creating various functionalized pyrrolidines. Additionally, it holds promise in medicinal chemistry as a precursor for synthesizing bioactive molecules, making it a valuable compound for researchers in both fields.
Uses
Used in Organic Synthesis:
(R)-tert-butyl 3-azidopyrrolidine-1-carboxylate is used as a building block for the synthesis of various functionalized pyrrolidines. Its unique structure and reactivity allow for the creation of a wide range of compounds with different properties and applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (R)-tert-butyl 3-azidopyrrolidine-1-carboxylate is used as a precursor for the synthesis of bioactive molecules. Its potential applications in this area stem from its ability to be modified and incorporated into more complex molecular structures, which can then be evaluated for their therapeutic properties.
Used in Research and Development:
(R)-tert-butyl 3-azidopyrrolidine-1-carboxylate is also utilized in research and development, particularly for exploring new reaction pathways and understanding the reactivity of azidopyrrolidine carboxylates. This knowledge can be applied to the design and synthesis of novel compounds with potential applications in various industries, including pharmaceuticals, materials science, and chemical engineering.
Check Digit Verification of cas no
The CAS Registry Mumber 143700-04-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,7,0 and 0 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 143700-04:
(8*1)+(7*4)+(6*3)+(5*7)+(4*0)+(3*0)+(2*0)+(1*4)=93
93 % 10 = 3
So 143700-04-3 is a valid CAS Registry Number.
143700-04-3Relevant articles and documents
HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF
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Paragraph 00507, (2016/05/02)
Disclosed are heteroaryl derivatives, pharmaceutical composition and uses in the manufacture of a medicine for treating respiratory diseases, especially for chronic obstructive pulmonary disease (COPD).
4-Aminothiourea prolinol tert-butyldiphenylsilyl ether: A chiral secondary amine-thiourea as organocatalyst for enantioselective anti-mannich reactions
Zhang, Hui,Chuan, Yongming,Li, Zhengyu,Peng, Yungui
supporting information; experimental part, p. 2288 - 2294 (2009/12/26)
anti-Selective Mannich reactions of N-p-methoxyphenyl (PMP)-protected α-iminoglyoxylate with unmodified aldehydes or ketones were effectively catalyzed by 4-aminothiourea prolinol tert-butyldiphenylsilyl ether. The reactions led to chiral β-amino carbonyl compounds in high yields (up to 94%), excellent diastereo- and enantioselectivities (up to 98% de and >99% ee). The study demonstrated for the first time that direct Mannich-type reactions of unmodified aldehydes or ketones to aiminoglyoxylate can be promoted by secondary amine-thiourea chiral organocatalyst.
METHOD AND COMPOSITIONS FOR TREATING HIV INFECTIONS
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, (2008/12/08)
Described herein are compounds and compositions that are useful in the treatment of HIV, AIDS, and AIDS-related diseases. In addition, compounds are described herein that are capable of inhibiting the dimerization of HIV proteases.
