1439367-66-4

Basic information

• Product Name: (2R,3S)-2-{[(cyclohexyloxy)carbonyl]amino}-3-hydroxybutanoic acid
• Synonyms: (2R,3S)-2-{[(cyclohexyloxy)carbonyl]amino}-3-hydroxybutanoic acid
• CAS NO: 1439367-66-4
• Molecular Weight: 245.276
• Mol File: 1439367-66-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2R,3S)-2-{[(cyclohexyloxy)carbonyl]amino}-3-hydroxybutanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S)-2-{[(cyclohexyloxy)carbonyl]amino}-3-hydroxybutanoic acid(1439367-66-4)
• EPA Substance Registry System: (2R,3S)-2-{[(cyclohexyloxy)carbonyl]amino}-3-hydroxybutanoic acid(1439367-66-4)

Safety Data

• Hazardous Substances Data: 1439367-66-4(Hazardous Substances Data)

Upstream product

• 1659-31-0 2,2'-dipyridyl carbonate 
• 632-20-2 D-Threonine 
• 108-93-0 cyclohexanol 

Downstream Products

• 1439366-80-9 cyclohexyl N-[(2S,3R)-2-methyl-4-oxooxetan-3-yl]-carbamate 

Relevant articles and documents

Synthesis, biological evaluation, and 3D QSAR study of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters as N -acylethanolamine acid amidase (NAAA) inhibitors

N-(2-Oxo-3-oxetanyl)carbamic acid esters have recently been reported to be noncompetitive inhibitors of the N-acylethanolamine acid amidase (NAAA) potentially useful for the treatment of pain and inflammation. In the present study, we further explored the

DISUBSTITUTED BETA-LACTONES AS INHIBITORS OF N-ACYLETHANOLAMINE ACID AMIDASE (NAAA)

The present invention provides compounds and pharmaceutical compositions for inhibiting N-acylethanolamine acid amidase (NAAA). Inhibition of NAAA is contemplated as a method to sustain the levels of palmitoylethanolamide (PEA) and oleylethanolamide (OEA), two substrates of NAAA, in conditions characterized by reduced concentrations of PEA and OEA. The invention also provides methods for treating inflammatory diseases and pain, and other disorders in which decreased levels of PEA and OEA are associated with the disorder.