144268-64-4Relevant articles and documents
Synthesis of Steroidal and Terpenoidal Extranucleo Thiazolidinones
Siddiqui, Abdul U.,Siddiqui, A. H.,Ramaiah, T. Sundara
, p. 85 - 86 (2007/10/02)
3-Oxo-5β-cholan-24-oic acid (1a), 3-oxo-lanost-8,24-diene (2a) and 3-oxo-olean-12-ene (3a) on reaction with hydrazine hydrate in alcoholic solution gave the respective 3-hydrazones (1b, 2b and 3b).Subsequent reaction of these 3-hydrazones with ammonium thiocyanate in benzene solution afforded 3-thiosemicarbazone derivatives (1c,2c and 3c) which undergo cyclisation with chloroacetic acid in the presence of anhydrous sodium acetate to yield 3--5β-cholan-24-oic acid (1d), 3-lanost-8,24-diene (2d) and 3-olean-12-ene (3d), respectively.
