1443244-49-2

Basic information

• Product Name: 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-((1S,4R)-4-[3-(4-methyl-4-triisopropylsilanyloxy-piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy]-1,2,3,4-tetrahydro-naphthalen-1-yl)-urea
• Synonyms: 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-((1S,4R)-4-[3-(4-methyl-4-triisopropylsilanyloxy-piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy]-1,2,3,4-tetrahydro-naphthalen-1-yl)-urea
• CAS NO: 1443244-49-2
• Molecular Weight: 805.151
• Mol File: 1443244-49-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-((1S,4R)-4-[3-(4-methyl-4-triisopropylsilanyloxy-piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy]-1,2,3,4-tetrahydro-naphthalen-1-yl)-urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-((1S,4R)-4-[3-(4-methyl-4-triisopropylsilanyloxy-piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy]-1,2,3,4-tetrahydro-naphthalen-1-yl)-urea(1443244-49-2)
• EPA Substance Registry System: 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-((1S,4R)-4-[3-(4-methyl-4-triisopropylsilanyloxy-piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy]-1,2,3,4-tetrahydro-naphthalen-1-yl)-urea(1443244-49-2)

Safety Data

• Hazardous Substances Data: 1443244-49-2(Hazardous Substances Data)

Upstream product

• 1443242-57-6 2,2,2-trifluoro-N-[(S)‐4‐carbonyl-1,2,3,4-tetrahydronaphthalen-1-yl]acetamide 
• 23357-52-0 (S)-1,2,3,4-tetrahydronapht-1-yl-amine 
• 1351997-20-0 (1R,4S)-aminoN-(S)-4-hydroxy-1,2,3,4-tetrahydronaphthalen-1-ol 
• 1443242-59-8 2,2,2-trifluoro-N-((1S,4R)-4-hydroxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-acetamide 
• 1443244-45-8 6-fluoro-3-(4-methyl-4-triisopropylsilanyloxy-piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridine 
• 1443244-43-6 1-(6-fluoro-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-4-methyl-piperidin-4-ol 
• 3970-68-1 4-methylpiperidin-4-ol 
• 406235-30-1 tert-butyl 4-hydroxy-4-methylpiperidine-1-carboxylate 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 317806-87-4 2,2,2-trichloroethyl 3-tert-butyl-1-p-tolyl-1H-pyrazol-5-ylcarbamate 
• 1443244-47-0 (1S,4R)-4-[3-(4-methyl-4-triisopropylsilanyloxy-piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy]-1,2,3,4-tetrahydro-naphthalen-1-ylamine 
• 1020036-49-0 3-chloro-6-fluoro-[1,2,4]triazolo[4,3-a]pyridine 
• 1019024-79-3 6-fluoro-[1,2,4] triazolo[4,3-a]pyridine 

Downstream Products

• 1443240-64-9 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-{(1S,4R)-4-[3-(4-hydroxy-4-methyl-piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy]-1,2,3,4-tetrahydro-naphthalen-1-yl}-urea 

Relevant articles and documents

KINASE INHIBITORS

Compounds of formula (I) or a pharmaceutically acceptable salt thereof: formula (I) wherein R2, W, A, Y and R1 are as defined in the specification, are p38 MAPK inhibitors, useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.