144343-34-0

Basic information

• Product Name: 3α,16β-dihydroxy-17,18-ditoluene-p-sulphonoxyaphidicolane
• CAS NO: 144343-34-0
• Molecular Weight: 646.866
• Mol File: 144343-34-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3α,16β-dihydroxy-17,18-ditoluene-p-sulphonoxyaphidicolane(CAS DataBase Reference)
• NIST Chemistry Reference: 3α,16β-dihydroxy-17,18-ditoluene-p-sulphonoxyaphidicolane(144343-34-0)
• EPA Substance Registry System: 3α,16β-dihydroxy-17,18-ditoluene-p-sulphonoxyaphidicolane(144343-34-0)

Safety Data

• Hazardous Substances Data: 144343-34-0(Hazardous Substances Data)

Upstream product

• 38966-21-1 Aphidicolin 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant articles and documents

Studies in Terpenoid Biosynthesis. Part 39. The Stereochemistry of the Relationship Between Substrate and Oxidant in the Hydroxylation of Aphidicolin at C-18 by Cephalosporium aphidicola

The preparation of some 3α,18-oxetane analogues of intermediates in the biosynthesis of aphidicolin is described.Their stereoselective labelling at C-18 with deuterium is reported.Biotransformation studies using these substrates with Cephalosporium aphidicola have shown that the 18-pro-R-hydrogen is removed in hydroxylation at this centre suggesting a Re stereochemical relationship between the substrate and oxidant for the normal hydroxylation at C-18.The X-ray crystallographic structure of 3α,18-oxetane 6 is presented and compared with that of aphidicolin 17-nor-16-ketone 13.