1445075-68-2

Basic information

• Product Name: (E)-methyl 2-(5-chloro-2-(3,3-diisopropyltriaz-1-en-1-yl)phenyl)-2,3,3,3-tetrafluoropropanoate
• Synonyms: (E)-methyl 2-(5-chloro-2-(3,3-diisopropyltriaz-1-en-1-yl)phenyl)-2,3,3,3-tetrafluoropropanoate
• CAS NO: 1445075-68-2
• Molecular Weight: 397.8
• Mol File: 1445075-68-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-methyl 2-(5-chloro-2-(3,3-diisopropyltriaz-1-en-1-yl)phenyl)-2,3,3,3-tetrafluoropropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-methyl 2-(5-chloro-2-(3,3-diisopropyltriaz-1-en-1-yl)phenyl)-2,3,3,3-tetrafluoropropanoate(1445075-68-2)
• EPA Substance Registry System: (E)-methyl 2-(5-chloro-2-(3,3-diisopropyltriaz-1-en-1-yl)phenyl)-2,3,3,3-tetrafluoropropanoate(1445075-68-2)

Safety Data

• Hazardous Substances Data: 1445075-68-2(Hazardous Substances Data)

Upstream product

• 392-41-6 methyl trifluoropropenoate 

Relevant articles and documents

Silver-mediated methoxycarbonyltetrafluoroethylation of arenes

In the presence of silver(I) fluoride, highly fluorinated olefins react readily under solvent-free conditions with arenes via CH-substitution. This transformation could be used to synthesize various methoxycarbonyltetrafluoroethylated aromatic triazenes and anisoles under high functional group tolerance. The method could be applied to the synthesis of a formal fluorinated bioisostere of the NSAID flurbiprofen. To the best of our knowledge, this is the first example which uses highly fluorinated olefins for the perfluoroalkylation of aromatic substrates.