1445993-96-3

Basic information

• Product Name: ethyl 4-bromo-6-methyl-7-oxo-1-toluenesulfonyl-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate
• Synonyms: ethyl 4-bromo-6-methyl-7-oxo-1-toluenesulfonyl-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate
• CAS NO: 1445993-96-3
• Molecular Weight: 453.313
• Mol File: 1445993-96-3.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: ethyl 4-bromo-6-methyl-7-oxo-1-toluenesulfonyl-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-bromo-6-methyl-7-oxo-1-toluenesulfonyl-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate(1445993-96-3)
• EPA Substance Registry System: ethyl 4-bromo-6-methyl-7-oxo-1-toluenesulfonyl-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate(1445993-96-3)

Safety Data

• Hazardous Substances Data: 1445993-96-3(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 116212-46-5 6-methyl-1H-pyrrolo<2,3-c>pyridin-7(6H)-one 
• 634-97-9 pyrrole-2-carboxyl acid 
• 116212-45-4 N-(2,2-dimethoxyethyl)-N-methyl-1H-pyrrole-2-carboxamide 
• 152684-30-5 5-bromo-2-methoxy-3-nitropyridine 
• 74-88-4 methyl iodide 
• 1361481-63-1 4-bromo-6-methyl-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one 
• 1622303-42-7 (E)-5-bromo-4-(2-(dimethylamino)vinyl)-1-methyl-3-nitropyridin-2(1H)-one 
• 1446237-40-6 5-bromo-1,4-dimethyl-3-nitro-1,2-dihydropyridin-2-one 
• 228410-90-0 2-hydroxy-5-bromo-4-methyl-3-nitropyridine 
• 100367-40-6 2-amino-3-nitro-4-methyl-5-bromopyridine 
• 6635-86-5 2-amino-4-methyl-3-nitropyridine 
• 67443-38-3 5-bromo-2-chloro-3-nitropyridine 
• 425380-38-7 4-bromo-7-chloro-3a,7a-dihydro-1H-pyrrolo[2,3-c]pyridine 

Relevant articles and documents

PYRROLE AMIDOPYRIDONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF

Disclosed are a pyrrole amidopyridone represented by general formula I, or a pharmaceutically acceptable salt thereof, or an enantiomer, a diastereomer, a tautomer, a solvate, a polymorph, or a prodrug thereof, a preparation method therefor and use thereof in pharmacy, the definition of each group being as described in the description.

COMPOUNDS COMPRISING N-METHYL-2-PYRIDONE, AND PHARMACEUTICALLY ACCEPTABLE SALTS

The present invention concerns compounds comprising N-methyl-2-pyridone, and pharmaceutically-acceptable salts and compositions of such compounds. Such compounds are useful in anti-inflammatory and anti-cancer therapies. Therefore, the present invention also concerns such compounds for use as medicaments, particularly for the treatment of inflammatory diseases and oncology.

PYRROLO[2,3-C]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE

Disclosed are a pyrrolo[2,3-c]pyridine derivative, a preparation method therefor, and use thereof in medicine. Specifically, disclosed are a pyrrolo[2,3-c]pyridine derivative as represented by general formula (1), a preparation method therefor, a pharmaceutical composition comprising the derivative, as well as use thereof as a BRD4 inhibitor in the treatment of related diseases such as cancers, inflammations, chronic liver diseases, diabetes, cardiovascular diseases and AIDS, each substituent in general formula (I) being same as defined in the description.