1446319-83-0

Basic information

• Product Name: C₂₂H₂₆FN₃O₃Si
• CAS NO: 1446319-83-0
• Molecular Weight: 427.551
• Mol File: 1446319-83-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₆FN₃O₃Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₆FN₃O₃Si(1446319-83-0)
• EPA Substance Registry System: C₂₂H₂₆FN₃O₃Si(1446319-83-0)

Safety Data

• Hazardous Substances Data: 1446319-83-0(Hazardous Substances Data)

Upstream product

• 526-47-6 5-fluoro-2,3-dimethyl-1H-indole 
• 1446319-68-1 5-fluoro-1,2,3-trimethyl-1H-indole 
• 1446319-71-6 9-fluoro-5a,6,10b-trimethyl-2-nitro-5a,6,10b,11-tetrahydrochromeno[2,3-b]indole 

Relevant articles and documents

Reactivity of tetrahydrochromeno[2,3-b]indoles: Chromic indicators of cyanide

The synthesis and reactivity of a tetrahydrochromeno[2,3-b]indoles are reported. Evidence for reversible ring-opening is based on H/D exchange and trapping experiments. These compounds readily undergo reaction with tetra-n-butylammonium cyanide. The cyanide reaction is 10-100× faster when the solution is irradiated with 350 nm light. Reaction with trimethylsilyl cyanide occurs only with UV irradiation demonstrating photoreactivity. The rate of tetrahydrochromeno[2,3-b]indole ring-opening is greater for (i) Me substitution at the hemiaminal carbon (compared to Ph), and (ii) substitution of fluorine at the 9-position of the indole. Under acidic conditions, the ring-opened indolium ion is observed. Copyright