14465-61-3

Basic information

• Product Name: 2,2-DIMETHYL-1,2-DIHYDRO-QUINOLINE
• Synonyms: 2,2-DIMETHYL-1,2-DIHYDRO-QUINOLINE
• CAS NO: 14465-61-3
• Molecular Formula: C₁₁H₁₃N
• Molecular Weight: 159.22762
• Mol File: 14465-61-3.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 256.286 °C at 760 mmHg
• Flash Point: 111.057 °C
• Appearance: liquid
• Density: 0.971 g/cm³
• Vapor Pressure: 0.016mmHg at 25°C
• Refractive Index: 1.53
• CAS DataBase Reference: 2,2-DIMETHYL-1,2-DIHYDRO-QUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DIMETHYL-1,2-DIHYDRO-QUINOLINE(14465-61-3)
• EPA Substance Registry System: 2,2-DIMETHYL-1,2-DIHYDRO-QUINOLINE(14465-61-3)

Safety Data

• Hazardous Substances Data: 14465-61-3(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron, 61, p. 155, 2005 DOI: 10.1016/j.tet.2004.10.035

InChI:InChI=1/C11H13N/c1-11(2)8-7-9-5-3-4-6-10(9)12-11/h3-8,12H,1-2H3

Upstream product

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Downstream Products

• 20364-30-1 2,2-dimethyl-1,2,3,4-tetrahydroquinoline 
• 179898-89-6 1-tert-butoxycarbonyl-1,2-dihydro-2,2-dimethylquinoline 
• 179898-88-5 1,2,3,4-tetrahydro-2,2,3-trimethylquinoline 
• 179899-03-7 (R/S)-3-ethyl-1,2,3,4-tetrahydro-2,2-dimethylquinoline 
• 179899-22-0 7-amino-1,2,3,4-tetrahydro-2,2-dimethylquinoline 
• 201541-36-8 1,2,3,4-tetrahydro-2,2-dimethyl-7-nitroquinoline 
• 179898-87-4 1-tert-butoxycarbonyl-1,2,3,4-tetrahydro-2,2-dimethyl-4-quinolinone 
• 88774-00-9 N-(2-trifluoromethylbenzoyl)-2,2-dimethyl-1,2,3,4-tetrahydroquinoline 

Relevant articles and documents

SUBSTITUTED, SATURATED AND UNSATURATED N-HETEROCYCLIC CARBOXAMIDES AND RELATED COMPOUNDS FOR THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

The invention provides substituted, saturated and unsaturated N-heterocyclic carboxamides and related compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., cancer, lysosomal storage disorder, neurodegenerative disorder, inflammatory disorder, in a patient.

Enantioselective epoxidation of dihydroquinolines by using iminium salt organocatalysts

The first examples of asymmetric epoxidation of dihydroquinoline substrates using iminium salt organocatalysts are reported. The 3,4-epoxytetrahydroquinoline products are obtained in good yields and with moderate to good enantioselectivities.

ALKOXYPHENYLPROPANOIC ACID DERIVATIVES

The present invention aims at provision of a novel compound having a GPR40 receptor function modulating action, which is useful as an insulin secretagogue, an agent for the prophylaxis or treatment of diabetes and the like. The compound represented by the formula: wherein each symbol is as defined in the description, a salt thereof, and a prodrug thereof of the present invention unexpectedly have a superior GPR40 receptor agonistic activity and superior properties as pharmaceutical products such as stability and the like, and can be safe and useful pharmaceutical agents as agents for the prophylaxis or treatment of GPR40 receptor-related pathology or diseases in mammals.