14470-31-6

Basic information

• Product Name: L-Valine, N-[N-[(phenylmethoxy)carbonyl]-L-phenylalanyl]-, 1,1-dimethylethyl ester
• CAS NO: 14470-31-6
• Molecular Formula: C26H34N2O5
• Molecular Weight: 454.566
• Mol File: 14470-31-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: L-Valine, N-[N-[(phenylmethoxy)carbonyl]-L-phenylalanyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Valine, N-[N-[(phenylmethoxy)carbonyl]-L-phenylalanyl]-, 1,1-dimethylethyl ester(14470-31-6)
• EPA Substance Registry System: L-Valine, N-[N-[(phenylmethoxy)carbonyl]-L-phenylalanyl]-, 1,1-dimethylethyl ester(14470-31-6)

Safety Data

• Hazardous Substances Data: 14470-31-6(Hazardous Substances Data)

Upstream product

• 1161-13-3 N-Cbz-L-Phe 
• 2528-15-6 D-valine t-butyl ester 
• 13518-40-6 L-valine tert-butylester hydrochloride 
• 540-88-5 acetic acid tert-butyl ester 
• 25613-60-9 Nα-carbobenzyloxy-L-phenylalanine N-carboxanhydride 
• 13211-31-9 tert-butyl L-valinate 
• 14470-30-5 N^α-benzyloxycarbonyl-L-phenylalanine anhydride 
• 2578-84-9 N-benzyloxycarbonyl-L-phenylalanine p-nitrophenyl ester 

Downstream Products

• 14611-28-0 (S)-tert-butyl 2-((S)-2-amino-3-phenylpropanamido)-3-methylbutanoate 
• 82213-52-3 Z-Phe-D-Val-Pro-OBu^t 
• 82213-53-4 Z-Phe-D-Val-Pro-OH 
• 82213-51-2 Z-Phe-Val-Pro-OBu^t 
• 55757-64-7 Z-Phe-Val-Pro-OH 
• 65710-40-9 Z-L-Val-L-Phe-L-Val-O-t-Bu 
• 17460-97-8 Z-Phe-D-Val-OH 
• 13123-00-7 (2S)-2-[((2S)-2-{[(benzyloxy)carbonyl]amino}-3-phenylpropanoyl)amino]-3-methylbutanoic acid 

Relevant articles and documents

Epimerization-Free C-Term Activation of Peptide Fragments by Ball Milling

Peptides were produced in high yields and, if any, very low epimerization, by mechanochemical coupling of peptide fragments containing highly epimerization-prone and/or highly hindered amino acids at C-term. Ball milling was clearly identified as the key element enabling one to obtain such results.

Rapid, one-pot synthesis of urethane-protected tripeptides

Urethane-protected tripeptides are synthesized in solution, without isolation of purification of intermediates, using urethane-protected N-carboxyanhydrides as coupling reagents and hydrogenation for removal of N-protection.