1447448-21-6Relevant articles and documents
Assembly of the nosiheptide A-ring: A fruitful lesson
Lu, Jin-Yong,Riedrich, Matthias,Wojtas, K.Philip,Arndt, Hans-Dieter
, p. 1300 - 1311 (2013)
The synthesis of a 28-membered thiopeptide macrocycle is described. Key steps are mild aza-Wittig thiazole ring closures, a scandium(III)-mediated regioselective ester hydrolysis, and a highly efficient macrolactam formation with its 3-hydroxypyridine nucleus orthogonally protected. Georg Thieme Verlag Stuttgart, New York.