144785-46-6

Basic information

• Product Name: 1,3-Dichloro-2-hydroxy-7-phenyl-quinolizin-4-one
• CAS NO: 144785-46-6
• Molecular Weight: 306.148
• Mol File: 144785-46-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3-Dichloro-2-hydroxy-7-phenyl-quinolizin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dichloro-2-hydroxy-7-phenyl-quinolizin-4-one(144785-46-6)
• EPA Substance Registry System: 1,3-Dichloro-2-hydroxy-7-phenyl-quinolizin-4-one(144785-46-6)

Safety Data

• Hazardous Substances Data: 144785-46-6(Hazardous Substances Data)

Upstream product

• 1008-88-4 3-phenylpyridine 
• 3200-96-2 2,3,4,4-tetrachloro-cyclobut-2-en-1-one 

Relevant articles and documents

Oxocarbons and related compounds; Part 18. The reaction of perchlorocyclobutenone with pyridines: A novel synthesis of 4H-4-quinolizinones

Heating of tetrachlorocyclobutenone (5) with the pyridines 6a-i followed by treatment with water affords 1,3-dichloro-2-hydroxy-4H-4-quinolizinones 7a, b, g-h and 1,3-dichloro-2-hydroxy-4-oxo-4H-quinolizinecarboxylates 7c-f. The reaction pathway has been secured by trapping 1,2,3-trichloro-8-(1,1-dimethylethyl)-4H-4-quinolizinone (11b) and by its successive conversion to 7b on heating with water.