144810-19-5

Basic information

• Product Name: 10-methyl-9,10-dihydroacridine-3,6-diamine
• Synonyms: 10-Methyl-9,10-dihydro-3,6-acridinediamine; 3,6-acridinediamine, 9,10-dihydro-10-methyl-; 3,6-diamino-10-methyl-9,10-dihydroacridine
• CAS NO: 144810-19-5
• Molecular Formula: C₁₄H₁₅N₃
• Molecular Weight: 225.289
• Mol File: 144810-19-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 480.3°C at 760 mmHg
• Flash Point: 240.2°C
• Density: 1.239g/cm³
• Vapor Pressure: 2.2E-09mmHg at 25°C
• Refractive Index: 1.704
• CAS DataBase Reference: 10-methyl-9,10-dihydroacridine-3,6-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 10-methyl-9,10-dihydroacridine-3,6-diamine(144810-19-5)
• EPA Substance Registry System: 10-methyl-9,10-dihydroacridine-3,6-diamine(144810-19-5)

Safety Data

• Hazardous Substances Data: 144810-19-5(Hazardous Substances Data)

Upstream product

• 837-73-0 3,6-diamino-10-methyl-acridinium 
• 2051-62-9 4'-biphenyl chloride 
• 86-40-8 acriflavine 

Relevant articles and documents

Genotoxicity assessment of new synthesized acridine derivative - 3,6-diamino-10-methyl-9,10-dihydroacridine

A new synthesized acridine derivative, 3,6-diamino-10-methyl-9,10-dihydroacridine (AcrH), was tested for in vitro reverse mutations with Salmonella TA strains, chromosome aberrations and sister chromatid exchanges (SCE) in human lymphocytes, and for in vivo chromosome aberrations in bone marrow of mice. Using the classic plate incorporation method, mutagenicity of AcrH in bacterial cells (TA97a, TA98, TA100 and TA102) was observed in the experiments performed with, and without, rat liver S9 metabolic activation. The reverse mutation assay showed no difference in mutagenic activity between AcrH and acriflavine (Acr+) in the test with TA97. The results of in vitro chromosome aberrations assay revealed potential clastogenicity. The test using macroculture of human lymphocytes induced mainly chromatid gaps. The experiments with human lymphocytes revealed SCE-inducing effect of AcrH and Acr+. In an in vivo study, AcrH given intraperitoneally to Balb/c mice did not cause any significant increase in the percentage of cells with aberrations compared to the negative control. Copyright (C) 1999 Elsevier Science B.V.

Efficient and Stable Photocatalytic Systems for Reductive Dechlorination of p-Chlorobiphenyl by Sodium Borohydride

Acridine Derivatives (9,10-dihydro-10-methylacridine and acriflavine) act as efficient and stable photocatalysts for reductive dechlorination of p-chlorobiphenyl as well as dehalogenation of bromochlorobenzenes with sodium borohydride in acetonitrile/H2O (9:1 v/v) at 298 K.In the case of acriflavine, the limiting quantum yield at irradiation wavelength λ = 350 nm has reached 0.63.