144818-69-9

Basic information

• Product Name: 2,2,2-trifluoro-N-(3-(4-methoxyphenyl)propyl)acetamide
• Synonyms: 2,2,2-trifluoro-N-(3-(4-methoxyphenyl)propyl)acetamide
• CAS NO: 144818-69-9
• Molecular Weight: 261.244
• Mol File: 144818-69-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,2,2-trifluoro-N-(3-(4-methoxyphenyl)propyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trifluoro-N-(3-(4-methoxyphenyl)propyl)acetamide(144818-69-9)
• EPA Substance Registry System: 2,2,2-trifluoro-N-(3-(4-methoxyphenyl)propyl)acetamide(144818-69-9)

Safety Data

• Hazardous Substances Data: 144818-69-9(Hazardous Substances Data)

Upstream product

• 36397-51-0 3-(4-methoxyphenyl)propan-1-amine hydrogen chloride 
• 76-05-1 trifluoroacetic acid 
• 36397-23-6 3-(4-methoxyphenyl)propylamine 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 125960-61-4 2,2,2-Trifluoro-N-[3-(4-methoxy-3-sulfamoyl-phenyl)-propyl]-acetamide 

Relevant articles and documents

N2-(2-METHOXYPHENYL)PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR CANCER PREVENTION OR TREATMENT CONTAINING SAME AS ACTIVE INGREDIENT

The present invention relates to a N2-(2-methoxyphenyl)pyrimidine derivative, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of cancer comprising the same as an active ingredient. The N2-(2-methoxyphenyl)pyrimidine derivative, the optical isomer thereof, or the pharmaceutically acceptable salt thereof of the present invention is very effective in suppressing anaplastic lymphoma kinase (ALK) activity and as a result it can improve the effectiveness of treatment on cancer cells having anaplastic lymphoma kinase (ALK) fusion proteins such as EML4-ALK and NPM-ALK, so that it can be effectively used as a pharmaceutical composition for preventing or treating cancer.