144882-57-5

Basic information

• Product Name: 1-Cyclohexyl-2-pyrrolidin-(2E)-ylidene-pent-4-ynylideneamine
• Synonyms: 1-Cyclohexyl-2-pyrrolidin-(2E)-ylidene-pent-4-ynylideneamine
• CAS NO: 144882-57-5
• Molecular Weight: 230.353
• Mol File: 144882-57-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Cyclohexyl-2-pyrrolidin-(2E)-ylidene-pent-4-ynylideneamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Cyclohexyl-2-pyrrolidin-(2E)-ylidene-pent-4-ynylideneamine(144882-57-5)
• EPA Substance Registry System: 1-Cyclohexyl-2-pyrrolidin-(2E)-ylidene-pent-4-ynylideneamine(144882-57-5)

Safety Data

• Hazardous Substances Data: 144882-57-5(Hazardous Substances Data)

Upstream product

• 872-32-2 2-methyl-1H-pyrroline 
• 766-05-2 cyclohexane carbonitrile 
• 106-96-7 propargyl bromide 

Downstream Products

• 144882-55-3 7-(cyclohexylcarbonyl)-5-methyl-2,3-dihydro-1H-pyrrolizine 

Relevant articles and documents

An efficient approach to pyrroles and N-bridgehead pyrroles by propargylation/cycloamination of 4-amino-1-azabutadiene derivatives

The thermal cycloamination of several propargyl-substituted 4-amino-1-azabutadienes 2 leading to 3-functionalized pyrroles 4-6 is described. Derivatives of pyrrolizidines 9 and indolizidines and azaazulenes 11-13 are synthesized directly from cyclic imines 7 and 10, respectively, in a multistep process that involves metalation with LDA, addition of a nitrile, carbanion trapping with propargyl bromide, and cycloamination. In all cases the more substituted imine nitrogen is involved in the cyclization reaction; such an experimental finding is supported by theoretical calculations.