145089-17-4

Basic information

• Product Name: L-Threonine, N-[[1-[3,5-bis(1,1-dimethylethyl)phenyl]-1-methylethoxy]carbonyl]-O-(1,1 -dimethylethyl)-
• CAS NO: 145089-17-4
• Molecular Formula: C26H43NO5
• Molecular Weight: 449.631
• Mol File: 145089-17-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Threonine, N-[[1-[3,5-bis(1,1-dimethylethyl)phenyl]-1-methylethoxy]carbonyl]-O-(1,1 -dimethylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Threonine, N-[[1-[3,5-bis(1,1-dimethylethyl)phenyl]-1-methylethoxy]carbonyl]-O-(1,1 -dimethylethyl)-(145089-17-4)
• EPA Substance Registry System: L-Threonine, N-[[1-[3,5-bis(1,1-dimethylethyl)phenyl]-1-methylethoxy]carbonyl]-O-(1,1 -dimethylethyl)-(145089-17-4)

Safety Data

• Hazardous Substances Data: 145089-17-4(Hazardous Substances Data)

Upstream product

• 4378-13-6 (O-tert-butyl)-L-threonine 
• 85313-39-9 Fluorameisensaeure-<1-(3,5-di-tert-butylphenyl)-1-methylethyl>ester 

Relevant articles and documents

SOLID PHASE SYNTHESIS OF A SOMATOSTATIN AMIDE ANALOGUE USING ACID LABILE t-BUMEOC PROTECTION AND AN ACID LABILE ANCHOR GROUP

The solid phase synthesis of an amidated somatostatin analogue based on the principle of differentiated acidolysis is described.The acid labile and smoothly cleavable t-Bumeoc moiety (1percent TFA/DCM) is used for temporary Nα-protection of D- and L-amino acids and amino>(4-methoxyphenyl)methyl>-2-methylphenoxy>acetic acid, attached to an aminomethylated polystyrene resin is used as acid sensitive linker of the solid carrier which releases the peptide in its amide form by treatment with TFA.Its preparation is described in detail.