145214-05-7 Usage
Description
2-(Tri-n-butylstannyl)oxazole is a synthetic building block characterized by its tri-n-butylstannyl group attached to the oxazole ring. 2-(TRI-N-BUTYLSTANNYL)OXAZOLE is known for its application in Stille coupling reactions, a type of palladium-catalyzed cross-coupling reaction in organic chemistry. The presence of the stannyl group makes it a versatile and valuable intermediate for the synthesis of various organic compounds.
Uses
Used in Pharmaceutical Industry:
2-(Tri-n-butylstannyl)oxazole is used as a synthetic building block for the development of new pharmaceutical compounds. Its application in Stille coupling reactions allows for the creation of complex molecular structures with potential therapeutic properties, contributing to the advancement of drug discovery and design.
Used in Chemical Research:
In the field of chemical research, 2-(Tri-n-butylstannyl)oxazole serves as a key intermediate for the synthesis of various organic molecules. Its use in Stille coupling reactions enables the formation of new carbon-carbon bonds, which are essential for the construction of complex molecular frameworks. 2-(TRI-N-BUTYLSTANNYL)OXAZOLE is particularly valuable in the synthesis of natural products, agrochemicals, and other specialty chemicals.
Used in Material Science:
2-(Tri-n-butylstannyl)oxazole is also utilized in the development of novel materials with unique properties. Its application in Stille coupling reactions allows for the synthesis of new organic compounds that can be used as building blocks for the creation of advanced materials with applications in various industries, such as electronics, energy, and aerospace.
Check Digit Verification of cas no
The CAS Registry Mumber 145214-05-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,2,1 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 145214-05:
(8*1)+(7*4)+(6*5)+(5*2)+(4*1)+(3*4)+(2*0)+(1*5)=97
97 % 10 = 7
So 145214-05-7 is a valid CAS Registry Number.
InChI:InChI=1/3C4H9.C3H2NO.Sn/c3*1-3-4-2;1-2-5-3-4-1;/h3*1,3-4H2,2H3;1-2H;/rC15H29NOSn/c1-4-7-12-18(13-8-5-2,14-9-6-3)15-16-10-11-17-15/h10-11H,4-9,12-14H2,1-3H3
145214-05-7Relevant articles and documents
THERAPEUTIC COMPOUNDS
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Paragraph 00442-00443, (2021/06/04)
The present disclosure relates to compounds of formula (I) and pharmaceutically acceptable salts thereof, and compositions and uses thereof. The compounds are useful as inhibitors of the YAP:TEAD protein:protein interaction. Also included are pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various YAP:TEAD-mediated disorders, including cancer.
COMPOUNDS
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Page/Page column 103-104, (2020/01/11)
A compound of formula (I), or a pharmaceutical salt thereof.
NOVEL ISOPHTHALATES AS BETA-SECRETASE INHIBITORS
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Page/Page column 43-44, (2010/11/23)
There is provided a series of substituted isophthalates of formula (I) or a stereoisomer thereof; or a pharmaceutically acceptable salt thereof, wherein W, R3, R5 and R6 as defined herein, their pharmaceutical compositions and methods of use. These novel compounds inhibit the processing of amyloid precursor protein (APP) by β-secretase and, more specifically, inhibit the production of Aβ-peptide. The present disclosure is directed to compounds useful in the treatment of neurological disorders related to β-amyloid production, such as Alzheimer's disease and other conditions affected by anti-amyloid activity.
