146137-33-9

Basic information

• Product Name: (4S)-4-phenyl-3-(3-phenylbutanoyl)oxazolidin-2-one
• Synonyms: (4S)-4-phenyl-3-(3-phenylbutanoyl)oxazolidin-2-one
• CAS NO: 146137-33-9
• Molecular Weight: 309.365
• Mol File: 146137-33-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (4S)-4-phenyl-3-(3-phenylbutanoyl)oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-4-phenyl-3-(3-phenylbutanoyl)oxazolidin-2-one(146137-33-9)
• EPA Substance Registry System: (4S)-4-phenyl-3-(3-phenylbutanoyl)oxazolidin-2-one(146137-33-9)

Safety Data

• Hazardous Substances Data: 146137-33-9(Hazardous Substances Data)

Upstream product

• 108-86-1 bromobenzene 
• 111292-75-2 (4S)-3-((2E)-2-butenoyl)-4-phenyl-1,3-oxazolidin-2-one 
• 98-80-6 phenylboronic acid 
• 99395-88-7 (S)-4-phenyl-2-oxazolidinone 
• 148766-15-8 (4S)-N-crotonyl-4-phenyloxazolidin-2-one 
• 100-58-3 phenylmagnesium bromide 
• 20989-17-7 (2S)-2-phenylglycinol 
• 2935-35-5 (S)-2-phenylglycine 
• 4593-90-2 3-phenylbutyric acid 
• 75-16-1 methylmagnesium bromide 
• 141209-95-2 (4S)-4-phenyl-3-[(2E)-3-phenylprop-2-enoyl]-1,3-oxazolidin-2-one 

Downstream Products

• 160636-94-2 (S)-3-((2R,3S)-2-Azido-3-phenyl-butyryl)-4-phenyl-oxazolidin-2-one 
• 128677-93-0 (2R)-azido-(3S)-phenylbutanoic acid 
• 59905-30-5 threo-D-(2R,3S)-β-methylphenylalanine 
• 148706-31-4 (S)-3-((2S,3S)-2-Bromo-3-phenyl-butyryl)-4-phenyl-oxazolidin-2-one 
• 772-14-5 (R)-3-phenylbutyric acid 

Relevant articles and documents

Palladium-Catalyzed Diastereoselective Synthesis of 3-Arylbutanoic Acid Derivatives

The first palladium-catalyzed diastereoselective conjugate addition of arylboronic acids to chiral imides is reported. The catalytic system employing 4-tert-butyloxazolidin-2-one as the chiral auxiliary in a mixed solvent system of MeOH/H2O (1:3) under an air atmosphere provides the optically active 3-arylbutanoic acid derivatives in excellent yields with high diastereoselectivity.

Diastereoselection in the conjugate additions of organocopper reagents to N-enoyloxazolidinones

A survey of conjugate additions of Yamamoto organocopper reagents to N- enoyl-4-substituted oxazolidinones is reported. Diastereofacial selectivity is reversed for 4-phenyl and 4-benzyloxazolidinones of the same relative configuration. Alkenylcopper reage

Diastereospecific tandem Michael-like addition/electrophilic bromination: A one-pot tandem asymmetric synthesis of precursors of unusual amino acids

A systematic series of key intermediates of unusual β-methyl-amino acids have been synthesized by using a modified Evans auxiliary in an asymmetric Michael-like reaction followed by direct bromination in a one-pot reaction.