146881-62-1

Basic information

• Product Name: 4-tert-butyl-3-cyano-6-methyl-2(1H)-pyridinone
• Synonyms: 4-tert-butyl-3-cyano-6-methyl-2(1H)-pyridinone
• CAS NO: 146881-62-1
• Molecular Weight: 190.245
• Mol File: 146881-62-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-tert-butyl-3-cyano-6-methyl-2(1H)-pyridinone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-tert-butyl-3-cyano-6-methyl-2(1H)-pyridinone(146881-62-1)
• EPA Substance Registry System: 4-tert-butyl-3-cyano-6-methyl-2(1H)-pyridinone(146881-62-1)

Safety Data

• Hazardous Substances Data: 146881-62-1(Hazardous Substances Data)

Upstream product

• 109-77-3 malononitrile 
• 254734-52-6 (Z)-4-Amino-5,5-dimethyl-hex-3-en-2-one 

Relevant articles and documents

Regioselective synthesis of 2(1H)-pyridinones from β-aminoenones and malononitrile. Reaction mechanism

The identification of some intermediates of the reactions between β- aminoenones and malononitrile to give 2(1H)-pyridinones has allowed us to obtain valuable information concerning its mechanism. These reactions begin with a conjugated addition of the nitrile to the enone followed by elimination. The compounds thus obtained cyclize to nonisolable 2H-pyran-2- imine. This afforded 2(1H)-pyridinones by ring opening to unsaturated aminoamides followed by cyclization (Dimroth-type rearrangement).