1480-96-2 Usage
Description
2-Methoxy-5-fluorouracil, also known as 5-Fluoro-4-hydroxy-2-methoxypyrimidine (CAS# 1480-96-2), is an organic compound with off-white solid properties. It is primarily used in the field of organic synthesis due to its unique chemical structure and reactivity.
Uses
Used in Organic Synthesis:
2-Methoxy-5-fluorouracil is used as a synthetic building block for the development of various chemical compounds. Its application in organic synthesis is attributed to its unique structure, which allows for further functionalization and the creation of a wide range of molecules with potential applications in different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Methoxy-5-fluorouracil is used as an intermediate in the synthesis of therapeutic agents, particularly those with potential anticancer properties. Its incorporation into drug molecules can enhance their efficacy and selectivity towards cancer cells, making it a valuable component in the development of novel cancer treatments.
Used in Research and Development:
2-Methoxy-5-fluorouracil is also utilized in research and development settings, where it serves as a key compound for studying the mechanisms of action, structure-activity relationships, and potential applications of various drug candidates. Its unique chemical properties make it an attractive candidate for exploring new avenues in drug discovery and development.
Flammability and Explosibility
Notclassified
Check Digit Verification of cas no
The CAS Registry Mumber 1480-96-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,8 and 0 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1480-96:
(6*1)+(5*4)+(4*8)+(3*0)+(2*9)+(1*6)=82
82 % 10 = 2
So 1480-96-2 is a valid CAS Registry Number.
InChI:InChI=1/C5H5FN2O2/c1-10-5-7-2-3(6)4(9)8-5/h2H,1H3,(H,7,8,9)
1480-96-2Relevant articles and documents
Composition of 5-fluorouracil and preparation method of composition
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Paragraph 0061; 0063; 0064; 0070, (2019/11/12)
The invention discloses a refining method of 5-fluorouracil. The method comprises the following steps: dissolving 5-fluorouracil into an organic solvent, preferably DMSO (dimethyl sulfoxide), and performing heating and stirring till dissolution; naturally cooling filtrate till a crystal is separated; performing filtration, washing filter cakes by using a polar solvent, and performing pumping and vacuum drying. By adopting the novel refining method, the content of impurities in the 5-fluorouracil can be reduced to 0.01% or less, the product purity is 99.98% or greater, and the refining yield isgreater than 70%. In addition, the refining method disclosed by the invention is simple in process, convenient in operation, low in production cost, high in product purity, stable in process and applicable to industrial production.
