148402-26-0Relevant articles and documents
3N-Methylbiphenylsulfonylurea and -carbamate substituted imidazo[4,5-b]pyridines. Potent antagonists of the ANG II AT1 receptors
Heitsch, Holger,Becker, Reinhard H.A.,Kleemann, Heinz-Werner,Wagner, Adalbert
, p. 673 - 678 (2007/10/03)
The synthesis and the SAR study of imidazo[4,5-b]pyridine biphenyl sulfonylureas and -carbamates as highly potent AT1-seIective ANG II receptor antagonists are described. Several members of this new class of antagonists efficiently inhibited the ANG II-induced presser response in pithed rats after iv and intraduodenal (id) administration.