14917-41-0

Basic information

• Product Name: 2',4',6',3,4-PENTAHYDROXYCHALCONE
• Synonyms: ERIODICTYOL CHALCONE;3,4,2',4',6'-PENTAHYDROXYCHALCONE;2',4',6',3,4-PENTAHYDROXYCHALCONE;PENTAHYDROXYCHALCONE,2',4',6',3,4-;PENTAHYDROXYCHALCONE,2',4',6',3,4-(SH);3,4,2'',4'',6''-PENTAHYDROXYCHALCONE WITH HPLC;PENTADECANE, n-(RG);(E)-3-(3,4-Dihydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one
• CAS NO: 14917-41-0
• Molecular Formula: C₁₅H₁₂O₆
• Molecular Weight: 288.25
• Mol File: 14917-41-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 595.9°Cat760mmHg
• Flash Point: 328.2°C
• Appearance: /
• Density: 1.584g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2',4',6',3,4-PENTAHYDROXYCHALCONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2',4',6',3,4-PENTAHYDROXYCHALCONE(14917-41-0)
• EPA Substance Registry System: 2',4',6',3,4-PENTAHYDROXYCHALCONE(14917-41-0)

Safety Data

• Hazardous Substances Data: 14917-41-0(Hazardous Substances Data)

Usage

General Description

2',4',6',3,4-Pentahydroxychalcone is a natural chemical compound found in certain plant species that has been studied for its potential medicinal properties. It is classified as a chalcone, a type of flavonoid compound known for its antioxidant and anti-inflammatory properties. 2',4',6',3,4-Pentahydroxychalcone has been found to have potential anti-cancer, anti-diabetic, and anti-inflammatory effects in various studies. It is also being investigated for its potential use in the development of new pharmaceutical drugs due to its favorable biological activities. Additionally, this compound has shown promise in the treatment of neurodegenerative diseases and has potential as a therapeutic agent for various health conditions.

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Downstream Products

• 4049-38-1 eriodictyol 
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Relevant articles and documents

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Natural and synthetic 2′-hydroxy-chalcones and aurones: Synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity

A series of 2′-hydroxy-chalcones and their oxidative cyclization products, aurones, have been synthesized and tested for their antioxidant and lipoxygenase inhibitory activity. The natural product aureusidin (31) was synthesized in high yield by a new approach. An extensive structure-relationship study was performed and revealed that several chalcones and aurones possess an appealing pharmacological profile combining high antioxidant and lipid peroxidation activity with potent soybean LOX inhibition.

DPPH radical scavenging reaction of hydroxy- and methoxychalcones

The DPPH radical scavenging activity of 2′,4′,6′- trihydroxy- and 2′-hydroxy-4′,6′-dimethoxychalcones carrying a 2,3- and 3,4-dihydroxylated, and 3,4,5-trihydroxylated B-ring was evaluated in alcoholic and non-alcoholic solvents. All test compounds scavenged more than two equivalent of radicals by a possible conversion to the corresponding B-ring quinones and in most cases subsequently underwent cyclization to aurones and flavanones, these being identified in the reaction solutions by an in situ NMR analysis. Interestingly, the reaction between 2′,3,4-trihydroxy-4′, 6′-dimethoxychalcone and the DPPH radical was significantly affected by the solvent used, which might be accounted for by the difference in readiness for cyclization to an aurone.