14933-09-6

Basic information

• Product Name: 3-(N,N-Dimethylmyristylammonio)propanesulfonate
• Synonyms: N-TETRADECYL-N N-DIMETHYL-3-AMMONIO-1-;zwittergent3-14;3-sulfopropylhexadecyldimethyl ammonium Betaine;dimethyl(3-sulfopropyl)tetradecylammonium hydroxi;Myristyl-dimethylammonium-3-sulfopropyl betaine;N-tetradecyl-N,N-dimethyl-3-ammonio-1-*propanesul;RALUFON DM;Tetradecanaminium-N,N-dimethyl-N-(3-sulfopropyl)-, hydroxide, inner salt
• CAS NO: 14933-09-6
• Molecular Formula: C₁₉H₄₁NO₃S
• Molecular Weight: 363.6
• EINECS: 239-003-9
• Product Categories: Pharmaceutical Raw Materials;Detergents;Sulfobetaines
• Mol File: 14933-09-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 246-248°C
• Flash Point: 110 °C
• Appearance: Dark blue to purple/Fine Powder
• Storage Temp.: 2-8°C
• Solubility: H2O: 1 M at 20 °C, clear, colorless
• Stability: Hygroscopic
• BRN: 6419727
• CAS DataBase Reference: 3-(N,N-Dimethylmyristylammonio)propanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(N,N-Dimethylmyristylammonio)propanesulfonate(14933-09-6)
• EPA Substance Registry System: 3-(N,N-Dimethylmyristylammonio)propanesulfonate(14933-09-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 3
• Hazardous Substances Data: 14933-09-6(Hazardous Substances Data)

Usage

Description

3-(N,N-Dimethylmyristylammonio)propanesulfonate, a zwitterionic surfactant belonging to the sulfobetaine class, is a white, shiny powder known for its unique chemical properties. It is widely utilized in various electrostatic ion chromatography techniques due to its ability to interact with different ions and molecules.

Uses

Used in Analytical Chemistry:
3-(N,N-Dimethylmyristylammonio)propanesulfonate is used as a component in the development of methods for quantifying perchlorate in biological samples. It aids in the separation and detection of perchlorate ions using capillary electrophoresis (CE) and capacitively coupled contactless conductivity detection, providing accurate and reliable results.
Used in Environmental Applications:
This surfactant is employed in the investigation and development of adsorbents for the elimination of water-soluble organic dyes. Its ability to interact with various ions and molecules makes it a valuable tool in the removal of pollutants from water sources, contributing to environmental sustainability.
Used in Pharmaceutical and Cosmetic Industries:
3-(N,N-Dimethylmyristylammonio)propanesulfonate is used as a surfactant in the formulation of pharmaceutical and cosmetic products. Its zwitterionic nature allows it to form stable complexes with various active ingredients, enhancing their solubility, bioavailability, and overall effectiveness.
Used in Electrostatic Ion Chromatography:
In the field of analytical chemistry, 3-(N,N-Dimethylmyristylammonio)propanesulfonate is used as a zwitterionic surfactant for various electrostatic ion chromatography techniques. It helps in the separation and analysis of charged species, providing accurate and reliable results in the study of complex mixtures.

InChI:InChI=1/C19H41NO3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-17-20(2,3)18-16-19-24(21,22)23/h4-19H2,1-3H3

Upstream product

• 1120-71-4 1,3-propanesultone 
• 112-75-4 N,N-dimethyl-n-tetradecylamine 

Relevant articles and documents

Surface and Antimicrobial Activity of Sulfobetaines

Sulfobetaines belong to the group of zwitterionic surfactants. They are electroneutral salts, which have in the same molecule, two ionic centers with different charge. Due to the specific structure they exhibit excellent properties such as good solubility in water and detergency. In this paper we present surface properties and adsorption parameters of sulfobetaines in water/air systems. From the adsorption isotherms the CMC value, the surface tension and surface pressure at the CMC as well as the efficiency of adsorption were determined. Physicochemical analyses of the data allowed for the further description of adsorption process. Results showed that sulfobetaines exhibit good surface properties especially low CMC and p20 values. Additionally the antimicrobial activity of sulfobetaines solutions against gram-positive and gram-negative bacteria were tested by the well-diffusion method. MIC values and growth kinetics were determined by microdilution method. Antimicrobial assays demonstrated that sulfobetaines can be good antibacterial agents, but the activity of surfactants strongly depends on alkyl chain length.

Synthesis, characterization and surface properties of series sulfobetaine surfactants

A series of surface active sulfo-propane betaines and sulfo-butane betaines were synthesized with high yields by the reaction of an appropriate N,N-dimethyl alkylamine with an excess of 1,3-propane sultone and 1,4-butane sultone. The structures were characterized by 1H-NMR spectroscopy and elemental analysis. The micellar properties of these compounds were determined by surface tension methods. Surface tension measurements also provide information about the dependence of the surface tension at the CMC (γcmc), pC20 (negative logarithm of the surfactant molar concentration C20 required to reduce the surface tension by 20 mN/m), the surface excess (Γmax) at air/solution interface, the minimum area per surfactant molecule at the air solution interface (A).