149489-04-3

Basic information

• Product Name: CARBAMIC ACID, (3-BROMO-2-PYRIDINYL)-, 1,1-DIMETHYLETHYL ESTER
• Synonyms: CARBAMIC ACID, (3-BROMO-2-PYRIDINYL)-, 1,1-DIMETHYLETHYL ESTER;(3-Bromo-pyridin-2-yl)-carbamic acid tert-butyl ester;tert-Butyl (3-bromopyridin-2-yl)carbamate;Carbamic acid,(3-bromo-2-pyridinyl)-,1,1-dimethylethyl ester (9Cl);Carbamic Acid, (3-Bromo-2-Pyridinyl)-, 1,1-Dimethylethyl Ester(WX637444)
• CAS NO: 149489-04-3
• Molecular Formula: C₁₀H₁₃BrN₂O₂
• Molecular Weight: 273.129
• Mol File: 149489-04-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: CARBAMIC ACID, (3-BROMO-2-PYRIDINYL)-, 1,1-DIMETHYLETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: CARBAMIC ACID, (3-BROMO-2-PYRIDINYL)-, 1,1-DIMETHYLETHYL ESTER(149489-04-3)
• EPA Substance Registry System: CARBAMIC ACID, (3-BROMO-2-PYRIDINYL)-, 1,1-DIMETHYLETHYL ESTER(149489-04-3)

Safety Data

• Hazardous Substances Data: 149489-04-3(Hazardous Substances Data)

Usage

General Description

CARBAMIC ACID, (3-BROMO-2-PYRIDINYL)-, 1,1-DIMETHYLETHYL ESTER is a chemical compound that belongs to the class of carbamic acid esters. It is commonly used as a pesticide and herbicide to control a wide range of pests and weeds. CARBAMIC ACID, (3-BROMO-2-PYRIDINYL)-, 1,1-DIMETHYLETHYL ESTER works by inhibiting essential enzymes in target organisms, which disrupts their biological processes and ultimately leads to their death. Due to its potential toxicity and hazardous nature, caution should be taken when handling and using this chemical. Additionally, it is important to follow all safety guidelines and regulations set forth by regulatory authorities when working with or disposing of this compound.

Upstream product

• 109-72-8 n-butyllithium 
• 38427-94-0 N-(tert-butoxycarbonyl)-2-aminopyridine 
• 106-93-4 ethylene dibromide 
• 39856-58-1 3-amino-2-bromopyridine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 13534-99-1 2-Amino-3-bromopyridine 
• 626-55-1 3-Bromopyridine 
• 36016-38-3 tert-Butyl N-hydroxycarbamate 

Downstream Products

• 13534-99-1 2-Amino-3-bromopyridine 
• 1288990-82-8 8-bromo-3-methylimidazo[1,2-a]pyridine 

Relevant articles and documents

Development of a Novel Process for the Kilogram-Scale Synthesis of Spiro[1 H-pyrido[2,3- d][1,3]oxazine-4,4′-piperidine]-2-one

Spiro[1H-pyrido[2,3-d][1,3]oxazine-4,4′-piperidine]-2-one (3) is a key building block in many biologically active compounds. The synthesis of this compound, as reported in the literature, is low-yielding. We have discovered and developed a robust, high-yielding process to generate 3 as a bis-HCl salt using alternative starting materials and reaction conditions. The developed process was successfully demonstrated on a kilogram scale. A two-batch kilo lab campaign generated the bis-HCl salt of 3 in >99 HPLC area percent purity and 77% overall yield.

Hydroarylation of Arenes via Reductive Radical-Polar Crossover

A photocatalytic system for the dearomative hydroarylation of benzene derivatives has been developed. Using a combination of an organic photoredox catalyst and an amine reductant, this process operates through a reductive radical-polar crossover mechanism where aryl halide reduction triggers a regioselective radical cyclization event, followed by anion formation and quenching to produce a range of complex spirocyclic cyclohexadienes. This light-driven protocol functions at room temperature in a green solvent system (aq. MeCN) without the need for precious metal-based catalysts or reagents or the generation of stoichiometric metal byproducts.

Method for inhibition of HIV related viruses

Treatment of AIDS, inhibition of the replication of HIV and related viruses thereof, and formulations using thiourea derivative compounds or salts thereof is disclosed. Also disclosed are novel thiourea derivative compounds.