14985-78-5

Basic information

• Product Name: tri-O-benzoyl-1-(6-methyl-purin-9-yl)-β-D-1-deoxy-ribofuranose
• Synonyms: tri-O-benzoyl-1-(6-methyl-purin-9-yl)-β-D-1-deoxy-ribofuranose
• CAS NO: 14985-78-5
• Molecular Weight: 578.581
• Mol File: 14985-78-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tri-O-benzoyl-1-(6-methyl-purin-9-yl)-β-D-1-deoxy-ribofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: tri-O-benzoyl-1-(6-methyl-purin-9-yl)-β-D-1-deoxy-ribofuranose(14985-78-5)
• EPA Substance Registry System: tri-O-benzoyl-1-(6-methyl-purin-9-yl)-β-D-1-deoxy-ribofuranose(14985-78-5)

Safety Data

• Hazardous Substances Data: 14985-78-5(Hazardous Substances Data)

Upstream product

• 2004-03-7 6-methylpurine 
• 14215-97-5 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose 
• 7306-68-5 6-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine 
• 92001-73-5 6-methyl-9-(tetrahydro-2-pyranyl)purine 

Downstream Products

• 14675-48-0 6-methyl-9-(β-D-ribofuranosyl)purine 

Relevant articles and documents

Improved synthesis of β-D-6-methylpurine riboside and antitumor effects of the β-D- and α-D-anomers

6-Methylpurine-β-D-riboside (β-D-MPR) has been synthesized by coupling 6-methylpurine and 1-O-acety1-2,3,5-tri-O-benzoyl-D-ribose using conditions that produce the β-D-anomer exclusively. The in vitro antitumor effects of β-D-MPR and 6-methyl-purine-α-D-riboside (α-D-MPR) in five human tumor cell lines showed that β-D-MPR was highly active (IC50 values ranging from 6 to 34 nM). a-D-MPR, although less active than β-D-MPR, also exhibited significant antitumor effects (IC50 values ranging from 1.47 to 4.83 μM).