150399-21-6 Usage
Description
Balsalazide disodium, also known as Colazal, is a prodrug of 5-aminosalicylic acid (mesalazine) with a carrier molecule of 4-aminobenzoyl-β-alanine. It is the dihydrate of the disodium salt of balsalazide and is used as an anti-inflammatory agent, particularly in the treatment of gastrointestinal conditions such as ulcerative colitis.
Uses
Used in Pharmaceutical Industry:
Balsalazide disodium is used as an anti-inflammatory agent for the treatment of ulcerative colitis. It is a prodrug that releases the active compound 5-aminosalicylic acid (mesalazine) in the large intestine, providing relief from inflammation and promoting healing.
Used in Gastrointestinal Treatment:
Balsalazide disodium is used as a prodrug for the targeted release of 5-aminosalicylic acid in the large intestine. This targeted release helps to reduce inflammation and alleviate symptoms associated with gastrointestinal conditions like ulcerative colitis.
Indications
Balsalazide disodium is delivered intact to the colon, where it is
cleaved by bacterial azoreduction to release equimolar
quantities of mesalamine, the therapeutically active
portion of the molecule, and 4-aminobenzoyl-β-alanine;
the latter compound is only minimally absorbed and is
largely inert.
Check Digit Verification of cas no
The CAS Registry Mumber 150399-21-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,3,9 and 9 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 150399-21:
(8*1)+(7*5)+(6*0)+(5*3)+(4*9)+(3*9)+(2*2)+(1*1)=126
126 % 10 = 6
So 150399-21-6 is a valid CAS Registry Number.
InChI:InChI=1/C17H15N3O6.2Na.2H2O/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23;;;;/h1-6,9,19H,7-8H2,(H,18,24)(H,22,23)(H,25,26);;;2*1H2/q;2*+1;;/p-2/b20-12-;;;;