15058-70-5

Basic information

• Product Name: benzyl (2S)-6-diazo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• Synonyms: benzyl (2S)-6-diazo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• CAS NO: 15058-70-5
• Molecular Weight: 317.368
• Mol File: 15058-70-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: benzyl (2S)-6-diazo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (2S)-6-diazo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate(15058-70-5)
• EPA Substance Registry System: benzyl (2S)-6-diazo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate(15058-70-5)

Safety Data

• Hazardous Substances Data: 15058-70-5(Hazardous Substances Data)

Upstream product

• 1254-56-4 benzyl (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 
• 3956-31-8 benzyl (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 
• 50269-19-7 C₂₃H₂₃N₃O₅S 
• 19912-14-2 (2S,5R,6R)-6-amino-2-(benzyloxycarbonyl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane p-toluenesulfonic acid 

Downstream Products

• 1374116-83-2 benzyl spiro[penicillanate-6,5'-(3-ethoxycarbonyl-2-pyrazoline)] 
• 1374116-76-3 benzyl spiro[penicillanate-6,5'-(3-ethoxycarbonyl-2-pyrazoline)] 
• 1374116-89-8 benzyl spiro[penicillanate-6,3'-(4,5-dimethoxycarbonyl-3H-pyrazole)] 
• 1374116-90-1 benzyl spiro[penicillanate-6,3'-(5-methoxycarbonyl-3H-pyrazole)] 
• 1374306-87-2 benzyl spiro[penicillanate-6,5'-(3-methoxycarbonyl-2-pyrazoline)] 
• 71972-80-0 benzyl spiro[penicillanate-6,5'-(3-methoxycarbonyl-2-pyrazoline)] 
• 1374116-82-1 benzyl spiro[penicillanate-6,5'-(3-cyano-2-pyrazoline)] 
• 1374116-75-2 benzyl spiro[penicillanate-6,5'-(3-cyano-2-pyrazoline)] 
• 1374116-84-3 benzyl spiro[penicillanate-6,5'-(3-acetyl-2-pyrazoline)] 
• 1374116-77-4 benzyl spiro[penicillanate-6,5'-(3-acetyl-2-pyrazoline)] 
• 1374116-97-8 benzyl spiro[penicillanate-6,4'-(7-phenyl-6,8-dioxo-2,3,7-triazabicyclo[3.3.0]oct-2-ene)] 
• 1374116-93-4 benzyl spiro[penicillanate-6,4'-(7-phenyl-6,8-dioxo-2,3,7-triazabicyclo[3.3.0]oct-2-ene)] 
• 1374116-98-9 benzyl spiro[penicillanate-6,4'-(7-methyl-6,8-dioxo-2,3,7-triazabicyclo[3.3.0]oct-2-ene)] 
• 1374116-94-5 benzyl spiro[penicillanate-6,4'-(7-methyl-6,8-dioxo-2,3,7-triazabicyclo[3.3.0]oct-2-ene)] 

Relevant articles and documents

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Synthesis Of 6β-Methoxy-6α-Hydroxymethylpenenms

6α-Hydroxymethyl-6β-methoxy-2-phenoxymethylpenem was synthesized from benzyl 6β-bromo-6α-methoxypenicillanate via radical addition at 6α-position of methyl tributyltinacrylate and tributyltinstyrene inter alia.The reaction sequence to penem proceeds via secopenicillanates according to established procedures.The good yield of the radical reaction and its stereoselectivity provide a useful entry to the 6α-substituted 6β-methoxypenems and in particular to the 6α-hydroxymethyl-6β-methoxypenems.

Preparation of 6α-Monosubstituted and 6,6-Disubstituted Penicillanates from 6-Diazopenicillanates: Reactions of 6-Diazopenicillanates with Alcohols, Thiols, Phenylseleninyl Compounds, and Allylic Sulphides, and their Analogues

Reactions of 6-diazapenicillanates (1) and (2) with a range of compounds, in some cases catalysed by BF3-Et2O or Cu(acac)2, have been investigated, and found to be useful for the synthesis of 6α-monosubstituted and 6,6-disubstituted penicillanates.Thus th