150807-03-7

Basic information

• Product Name: (2Z,8S,9R)-10-(tert-butyldiphenylsilyloxy)-8,9-epoxy-3-methyl-4,6-decadiyn-2-en-1-ol
• Synonyms: (2Z,8S,9R)-10-(tert-butyldiphenylsilyloxy)-8,9-epoxy-3-methyl-4,6-decadiyn-2-en-1-ol
• CAS NO: 150807-03-7
• Molecular Weight: 430.619
• Mol File: 150807-03-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2Z,8S,9R)-10-(tert-butyldiphenylsilyloxy)-8,9-epoxy-3-methyl-4,6-decadiyn-2-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2Z,8S,9R)-10-(tert-butyldiphenylsilyloxy)-8,9-epoxy-3-methyl-4,6-decadiyn-2-en-1-ol(150807-03-7)
• EPA Substance Registry System: (2Z,8S,9R)-10-(tert-butyldiphenylsilyloxy)-8,9-epoxy-3-methyl-4,6-decadiyn-2-en-1-ol(150807-03-7)

Safety Data

• Hazardous Substances Data: 150807-03-7(Hazardous Substances Data)

Upstream product

• 144629-83-4 Butyric acid (2R,3S)-3-(2,2-dibromo-vinyl)-oxiranylmethyl ester 
• 144540-67-0 Butyric acid (2R,3S)-3-bromoethynyl-oxiranylmethyl ester 
• 6153-05-5 (Z)-3-methylpent-2-en-4-ynol 
• 150852-27-0 5-bromo-1-tert-butyldiphenylsilyloxy-2,3-epoxypent-4-yne 

Relevant articles and documents

A general access to optically pure epoxypolyynes: Asymmetric synthesis of antifeedant natural products

A general asymmetric approach toward cis-epoxypolyynes is described using optically pure (2R, 3S)-5-bromo-2,3-epoxy-4-pentyn-1-ol 1a as the key intermediate. From this intermediate, the synthesis of 2 epoxy polyyne natural products was carried out in 6 steps with a 42% overall yield.