15116-41-3

Basic information

• Product Name: (E)-N-(3-METHOXY-PHENYL)-3-PHENYL-ACRYLAMIDE
• Synonyms: (E)-N-(3-METHOXY-PHENYL)-3-PHENYL-ACRYLAMIDE;m-Cinnamanisidide;N-(3-Methoxyphenyl)-3-phenylpropenamide
• CAS NO: 15116-41-3
• Molecular Formula: C₁₆H₁₅NO₂
• Molecular Weight: 253.2958
• Mol File: 15116-41-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (E)-N-(3-METHOXY-PHENYL)-3-PHENYL-ACRYLAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-N-(3-METHOXY-PHENYL)-3-PHENYL-ACRYLAMIDE(15116-41-3)
• EPA Substance Registry System: (E)-N-(3-METHOXY-PHENYL)-3-PHENYL-ACRYLAMIDE(15116-41-3)

Safety Data

• Hazardous Substances Data: 15116-41-3(Hazardous Substances Data)

Usage

Description

(E)-N-(3-METHOXY-PHENYL)-3-PHENYL-ACRYLAMIDE is a chemical compound with the formula C17H15NO2, characterized by a molecular weight of 277.30 g/mol. This acrylamide derivative features a phenyl group and a methoxyphenyl group attached to an acrylamide moiety, which endows it with both aromatic and double bond functional groups. Its structural attributes and potential biological activities make it a promising candidate for applications in medicinal chemistry and drug discovery.

Uses

Used in Organic Synthesis:
(E)-N-(3-METHOXY-PHENYL)-3-PHENYL-ACRYLAMIDE is utilized as a building block in organic synthesis for the preparation of various organic compounds and pharmaceutical intermediates. Its unique structure allows for the creation of a wide range of molecules with potential applications in different fields.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (E)-N-(3-METHOXY-PHENYL)-3-PHENYL-ACRYLAMIDE is used as a starting material for the development of new drugs. Its structural features and potential biological activities make it a valuable component in the design and synthesis of pharmaceuticals with specific therapeutic targets.
Used in Drug Discovery:
(E)-N-(3-METHOXY-PHENYL)-3-PHENYL-ACRYLAMIDE also plays a role in drug discovery, where it can be employed to explore its potential as a lead compound for the treatment of various diseases. Its aromatic and double bond functional groups offer opportunities for further chemical modifications to enhance its pharmacological properties and effectiveness.

Upstream product

• 102-92-1 cinnamoyl chloride 
• 536-90-3 m-Anisidine 
• 621-82-9 Cinnamic acid 

Downstream Products

• 70500-72-0 7-hydroxy-1H-quinolin-2-one 
• 203395-59-9 7–(4-bromobutoxy)quinolin-2(1H)-one 
• 1354030-20-8 7-(4-(4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl)butoxy)quinolin-2(1H)-one 
• 1354030-31-1 7-(4-(4-(2-methoxyphenyl)-1,4-diazepan-1-yl)butoxy)quinolin-2(1H)-one 
• 1354030-37-7 7-(4-(4-(2-ethoxyphenyl)-1,4-diazepan-1-yl)butoxy)quinolin-2(1H)-one 
• 1076199-59-1 7–(3-bromopropoxy)quinolin-2(1H)-one 
• 1354030-38-8 7-(3-(4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl)propoxy)quinolin-2(1H)-one 
• 1354030-42-4 7-(4-(4-(2-isopropoxyphenyl)-1,4-diazepan-1-yl)butoxy)quinolin-2(1H)-one 
• 23981-26-2 7-methoxyquinolin-2(1H)-one 
• 49609-15-6 2-chloro-7-methoxyquinoline 

Relevant articles and documents

TRIAZOLO-PYRAZINE DERIVATIVES USEFUL IN THE TREATMENT OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM

Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, including, but not limited to, e.g., neurological disorders, psychosis, schizophrenia, obesity, and diabetes.

FUNCTIONALLY SELECTIVE LIGANDS OF DOPAMINE D2 RECEPTORS

The present invention relates to novel functionally selective ligands of dopamine D2 receptors, including agonists, antagonists, and inverse agonists. The invention further relates to the use of these compounds for treating central nervous system disorders related to D2 receptors.