152141-78-1

Basic information

• Product Name: (S)-1,1,1-trifluoro-2-phenylbut-3-ene-2-ol
• Synonyms: (S)-1,1,1-trifluoro-2-phenylbut-3-ene-2-ol
• CAS NO: 152141-78-1
• Molecular Weight: 202.176
• Mol File: 152141-78-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-1,1,1-trifluoro-2-phenylbut-3-ene-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1,1,1-trifluoro-2-phenylbut-3-ene-2-ol(152141-78-1)
• EPA Substance Registry System: (S)-1,1,1-trifluoro-2-phenylbut-3-ene-2-ol(152141-78-1)

Safety Data

• Hazardous Substances Data: 152141-78-1(Hazardous Substances Data)

Upstream product

• 141946-97-6 (+)-1,1,1-trifluoro-2-phenylbut-3-yn-2-yl acetate 
• 434-45-7 2,2,2-Trifluoroacetophenone 
• 16753-62-1 methylvinyldimethoxysilane 
• 88445-11-8 (R)-4,4,4-trifluoro-3-phenyl-3-hydroxybutyne 

Downstream Products

• 17257-70-4 (R)-α-hydroxy-α-trifluoromethylphenyl acetic acid 
• 52356-09-9 3-Phenyl-3-hydroxy-4.4.4-trifluoro-buttersaeure 
• 151990-50-0 (2R,3S)-1,1,1-trifluoro-2-phenyl-3,4-epoxybutane-2-ol 

Relevant articles and documents

Catalytic enantioselective alkenylation and phenylation of trifluoromethyl ketones

Catalytic enantioselective alkenylation and phenylation of trifluoromethyl ketones are described. High enantioselectivity (up to 84% ee) was produced in an alkenylation of aryl trifluoromethyl ketones using a CuF-DTBM-SEGPHOS complex as the catalyst (5-10

The synthesis of (R)-γ-phenyl-γ-(trifluoromethyl)-butyrolactone and (2R,3S)-1,1,1-trifluoro-2-methoxy-2-phenyl-3,4-epoxybutane in homochiral forms

(R)-γ-Phenyl-γ-(trifluoromethyl)-butyrolactone (1) and (2R,3S)-1,1,1-trifluoro-2-methoxy-2-phenyl-3,4-epoxybutane (2) have been prepared in high optical purity from the tertiary (S)-(3)-acetate which was resolved using the lipase from Candida cylindracea.