152154-28-4 Usage
Description
Dexamethasone b-D-Glucuronide is a glucuronide conjugate of the anti-inflammatory corticosteroid Dexamethasone. It is a derivative that has been modified to enhance its delivery and targeting to specific areas in the body, particularly the colon.
Uses
Used in Pharmaceutical Industry:
Dexamethasone b-D-Glucuronide is used as a prodrug for the targeted delivery of Dexamethasone, an anti-inflammatory corticosteroid, to the colon. This targeted approach helps to reduce systemic side effects and increase the local concentration of the drug at the site of inflammation, providing more effective treatment for colonic conditions such as inflammatory bowel disease.
Check Digit Verification of cas no
The CAS Registry Mumber 152154-28-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,1,5 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 152154-28:
(8*1)+(7*5)+(6*2)+(5*1)+(4*5)+(3*4)+(2*2)+(1*8)=104
104 % 10 = 4
So 152154-28-4 is a valid CAS Registry Number.
InChI:InChI=1/C28H37FO11/c1-12-8-16-15-5-4-13-9-14(30)6-7-25(13,2)27(15,29)17(31)10-26(16,3)28(12,38)18(32)11-39-24-21(35)19(33)20(34)22(40-24)23(36)37/h6-7,9,12,15-17,19-22,24,31,33-35,38H,4-5,8,10-11H2,1-3H3,(H,36,37)/t12-,15?,16?,17+,19+,20+,21-,22+,24-,25+,26+,27?,28+/m1/s1
152154-28-4Relevant articles and documents
Albumin conjugates containing a glucuronic linker
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Page/Page column 4-5, (2008/06/13)
Described are conjugates comprising (a) a pharmacolocically active drug, preferably a corticosteroid, (b) a glucuronic acid and (c) an albumin. Said conjugates are suitable for the treatment/prevention of particular diseases, preferably inflammatory diseases.
