15217-53-5Relevant articles and documents
A facile one-pot synthesis of 1-substituted tetrazole-5-thiones and 1-substituted 5-alkyl(aryl)sulfanyltetrazoles from organic isothiocyanates
Han, Sam Yong,Lee, Je Woo,Kim, Hee-Jung,Kim, Yong-Joo,Lee, Soon W.,Gyoung, Young Soo
experimental part, p. 55 - 59 (2012/03/09)
Treatments of organic isothiocyanates (R-NCS) with NaN3 in the presence of pyridine in water at room temperature gave corresponding various organic tetrazole-thiones, [S=CN4(R)] (R = alkyl or aryl). Isolated products are obtained as white or yellow solids in good yields (76-97%). The molecular structure by X-ray diffraction study for one of products shows the proposed formation. In addition, one-pot synthesis of 1- substituted 5-alkyl(or aryl)sulfanyltetrazoles has been demonstrated. Addition of alkyl or aryl halides into the mixture of organic isothiocyanates, NaN3, and pyridine in water at room temperature exclusively formed 1- substituted 5-alkyl(or aryl)sulfanyltetrazoles (S-derivatives) in high yields.
Cyclized substituted thioureas. II. Preparation of some 1-substituted 1,2,3,4-tetrazole-5-thiones.
ORTH,JONES
, p. 862 - 864 (2007/10/04)
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