152237-41-7 Usage
Description
C13H20N2O4, also known as D,L-Dropropizine N,N-Dioxide, is an impurity found in Dropropizine (D681495), which is a therapeutic agent used as a cough suppressant and central sedative. C13H20N2O4 has a molecular structure consisting of 13 carbon atoms, 20 hydrogen atoms, 2 nitrogen atoms, and 4 oxygen atoms.
Uses
Used in Pharmaceutical Industry:
C13H20N2O4 is used as an impurity in the production of Dropropizine, a cough suppressant and central sedative therapeutic agent. Its presence in the final product may affect the efficacy and safety of the medication, so it is essential to monitor and control its levels during the manufacturing process.
Used in Quality Control and Regulatory Compliance:
C13H20N2O4 is used as a reference compound for quality control and regulatory compliance in the pharmaceutical industry. By analyzing its presence and concentration in Dropropizine products, manufacturers can ensure that their products meet the required safety and efficacy standards.
Used in Research and Development:
C13H20N2O4 serves as a valuable compound for researchers in the pharmaceutical industry, as it can be used to study the effects of impurities on the overall performance of therapeutic agents. This knowledge can help in the development of more effective and safer medications.
Check Digit Verification of cas no
The CAS Registry Mumber 152237-41-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,2,3 and 7 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 152237-41:
(8*1)+(7*5)+(6*2)+(5*2)+(4*3)+(3*7)+(2*4)+(1*1)=107
107 % 10 = 7
So 152237-41-7 is a valid CAS Registry Number.
152237-41-7Relevant articles and documents
A sensitive kinetic spectrophotometric determination of cefprozil and dropropizine in bulk and in dosage forms
Abdel-Gawad, Fatma M.,Mostafa, Carmen S.,Abdel-Hamid, Safaa M.,Abdel-Moaty, Mona M.,Abbas, Nagat A.
, p. 631 - 643 (2013/05/09)
A SIMPLE, accurate and sensitive kinetic spectrophotometric method is described for analysis of cefprozil and dropropizine. The method is based on kinetic investigations of the oxidation reaction of the drugs with alkaline potassium permanganate (KMnO4) at room temperature. The reaction is monitored spectrophotometrically by measuring the rate of change of absorbance of the resulting manganate species at 610 or 608 nm for cefprozil or dropropizine, respectively, with time. The two calibration curves at fixed-time method for the two drugs are utilized for the assay of drugs in the concentration ranges of 1.0-8.0 and 0.2-2.0 μg ml-1 for cefprozil and dropropizine, respectively. The results are optimized and validated statistically and through recovery studies. The method has been successfully applied to the determination of cefprozil and dropropizine in pharmaceutical preparations. The results obtained are compared statistically with those given by the reference method. A proposal of the oxidation reaction pathway is postulated.
